ASD

GO:0050994 regulation of lipid catabolic process (31)

GeneInput weightStandardRank
CNR10.25129
PRKCE--204
ADORA1--960
AKT10.2511020
IRS2--11300
IRS1--11374
ADRA2A0.2511399
PDE3B--3819
AKT2--13912
PPARA--4177
ANGPTL3--5089
CIDEA--6211
TWIST1--16980
FABP1--10047
HCAR2--10053
AADAC--10634
GIMAP5--10690
IL1B--110818
APOC2--13818
APOA5--113831
APOA2--14659
TNF0.25115243
APOC3--20262
MTOR--21095
ABHD5--121568
INS--122047
APOA4--22292
APOC1--23668
CPT1A--23997
MLYCD--24621
PNPLA2--24660

Network

GO:0050994

Network
Enrichment
NameDescriptionExternal IDs
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
IRS2insulin receptor substrate 2 Entrez:8660  HPRD: 02878  HGNC: 6126  Ensembl: ENSG00000185950 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CNR1cannabinoid receptor 1 (brain)
PRKCEprotein kinase C, epsilon
ADORA1adenosine A1 receptor
AKT1v-akt murine thymoma viral oncogene homolog 1
IRS2insulin receptor substrate 2
Query geneGeneGene descriptionEdge score
CNR1CNR1cannabinoid receptor 1 (brain)
PRKCEPRKCEprotein kinase C, epsilon
ADORA1ADORA1adenosine A1 receptor
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
IRS2IRS2insulin receptor substrate 2

Troyanskaya Laboratory - Princeton University