ASD

GO:0010923 negative regulation of phosphatase activity (7)

GeneInput weightStandardRank
TGFB2--834
FKBP1A--1284
FKBP1B--2346
PPP2R4--2609
TIPRL--4308
NCKAP1L--23771
MASTL--23970

Network

GO:0010923

Network
Enrichment
NameDescriptionExternal IDs
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
FKBP1AFK506 binding protein 1A, 12kDa Entrez:2280  Ensembl: ENSG00000088832  HGNC: 3711  HPRD: 01741 
FKBP1BFK506 binding protein 1B, 12.6 kDa Entrez:2281  Ensembl: ENSG00000119782  HPRD: 02795  HGNC: 3712 
PPP2R4protein phosphatase 2A activator, regulatory subunit 4 Entrez:5524  HPRD: 02858  HGNC: 9308  Ensembl: ENSG00000119383 
TIPRLTIP41, TOR signaling pathway regulator-like (S. cerevisiae) Entrez:261726  HGNC: 30231  HPRD: 14608  Ensembl: ENSG00000143155 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
TGFB2transforming growth factor, beta 2
FKBP1AFK506 binding protein 1A, 12kDa
FKBP1BFK506 binding protein 1B, 12.6 kDa
PPP2R4protein phosphatase 2A activator, regulatory subunit 4
TIPRLTIP41, TOR signaling pathway regulator-like (S. cerevisiae)
Query geneGeneGene descriptionEdge score
TGFB2TGFB2transforming growth factor, beta 2
FKBP1AFKBP1AFK506 binding protein 1A, 12kDa
FKBP1BFKBP1BFK506 binding protein 1B, 12.6 kDa
PPP2R4PPP2R4protein phosphatase 2A activator, regulatory subunit 4
TIPRLTIPRLTIP41, TOR signaling pathway regulator-like (S. cerevisiae)

Troyanskaya Laboratory - Princeton University