ASD

GO:0018212 peptidyl-tyrosine modification (38)

GeneInput weightStandardRank
DYRK1A1.01306
PDGFRA--1320
RELN1.01626
FYN--932
ABI2--986
KIT--11026
PRLR0.2511393
ABL1--2404
PTK20.2512488
SRC--2825
PTK2B--3063
CLK2--3295
DDR1--3647
WEE1--4406
CLK1--5674
INSR--15872
CLK4--6119
ABI1--6421
IL12RB2--6959
CLK3--7515
ABL2--8082
GHR--110098
TPST1--11193
FER--12719
F2--118599
JAK2--119561
OSM--19580
F2R--20036
JAK3--20340
PDGFB--21071
STAT5A--21176
FES--21831
BTK--122251
PDGFRB--23242
LCK--24753
TPST2--24838
STAT1--25107
EFEMP1--25366

Network

GO:0018212

Network
Enrichment
NameDescriptionExternal IDs
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A Entrez:1859  HPRD: 09018  HGNC: 3091  Ensembl: ENSG00000157540 
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide Entrez:5156  Ensembl: ENSG00000134853  HPRD: 01429  HGNC: 8803 
RELNreelin Entrez:5649  HGNC: 9957  Ensembl: ENSG00000189056  HPRD: 02742 
FYNFYN oncogene related to SRC, FGR, YES Entrez:2534  HGNC: 4037  Ensembl: ENSG00000010810  HPRD: 00655 
ABI2abl-interactor 2 Entrez:10152  Ensembl: ENSG00000138443  HGNC: 24011 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide
RELNreelin
FYNFYN oncogene related to SRC, FGR, YES
ABI2abl-interactor 2
Query geneGeneGene descriptionEdge score
DYRK1ADYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptide
RELNRELNreelin
FYNFYNFYN oncogene related to SRC, FGR, YES
ABI2ABI2abl-interactor 2

Troyanskaya Laboratory - Princeton University