ASD

GO:0042445 hormone metabolic process (142)

GeneInput weightStandardRank
PCSK2--217
CACNA1A--1270
PDGFRA--1320
NR3C1--496
CRH--563
DIO2--625
PCSK1--898
MED1--1034
PCSK6--1035
SCG50.2511173
SCHIP1--1178
CYP26B1--1734
ESR10.2511791
FOXA1--1990
YWHAH--2009
PCSK1N--2078
CPE--2149
CGA0.2512258
TSHB--2368
ASMTL--2405
STAT5B--2593
CRHBP--2688
TIPARP--2888
SAFB--2899
CYP26A1--3009
RBP4--3448
FOXE3--13688
ALDH1A2--3771
CRYM--3820
CYP19A10.2513823
CACNA1H1.013855
FOXE1--13900
PLEKHA1--3930
CYP17A10.2513984
DIO3--4145
GHRHR--4237
FURIN--4605
PRLHR--4669
CORIN--4683
HSD3B2--4818
TH0.2514933
SRD5A10.2514966
LRAT--15055
CYP1A10.2515067
SRD5A20.2515363
AANAT0.2515448
ADH7--5526
CHST8--5529
AKR1D1--15546
HSD3B1--5560
TPH20.2515693
CYP26C1--5830
CHST9--5902
DDC0.2515929
NGF0.2516229
SULT1E1--6341
TPO--16347
ALDH8A1--6351
TPH10.2516460
CYP11B10.2516613
SDR16C5--6965
UGT1A8--6979
REN--17086
DUOX1--7090
RDH12--17538
SLC5A5--17711
CYP11A10.2518063
PNMT--8605
STAR--8811
HSD11B10.2518910
AKR1C4--8941
RDH10--9300
CGB7--9343
HSD17B6--9498
GCNT4--9812
HSD11B2--9892
CYP3A4--9925
HSD17B30.2519988
ACE--10304
RDH8--10339
ECE2--10348
DBH0.25110495
BCO2--10506
PCSK7--10515
ASMT0.25110532
RBP1--10542
SULT1B1--10710
KLK6--10748
DHRS2--11471
IYD--11474
DIO1--11488
AFP--11538
DUOX2--111733
ADH4--11856
LEP0.25111864
UGT2B4--11987
SERPINA6--12381
FSHB0.25112923
PCSK5--13062
FGF2--13150
AGT--113305
CYP21A20.25113362
COMT0.25113475
SCARB1--13530
CYP11B2--13660
CGB5--14205
SLCO4A1--14525
POMC0.25114990
UGT2B11--15201
CGB8--15211
SGPL1--15362
IQCJ-SCHIP1--17789
UGT1A7--18533
TG--18556
SHH--118571
DHRS9--18976
UGT1A9--19030
LHB0.25119520
HSD17B1--19915
SRD5A3--120013
BACE2--20446
ECE1--120540
ADM--21106
RDH11--21301
HSD17B20.25121493
ALDH1A3--21739
WNT4--21809
CGB--22000
STARD5--22138
AKR1B1--22159
CYP1B10.25122210
UGT1A1--122467
CRABP2--22763
HSD17B11--22986
ALDH9A1--23032
UGT1A3--23330
DHRS3--25202
ATP6AP2--25361
HSD17B8--25429
IDE--25443
RETSAT--25533
SCPEP1--25678

Network

GO:0042445

Network
Enrichment
NameDescriptionExternal IDs
PCSK2proprotein convertase subtilisin/kexin type 2 Entrez:5126  Ensembl: ENSG00000125851  HGNC: 8744  HPRD: 01202 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide Entrez:5156  Ensembl: ENSG00000134853  HPRD: 01429  HGNC: 8803 
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
CRHcorticotropin releasing hormone Entrez:1392  Ensembl: ENSG00000147571  HPRD: 07172  HGNC: 2355 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PCSK2proprotein convertase subtilisin/kexin type 2
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
CRHcorticotropin releasing hormone
Query geneGeneGene descriptionEdge score
PCSK2PCSK2proprotein convertase subtilisin/kexin type 2
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptide
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
CRHCRHcorticotropin releasing hormone

Troyanskaya Laboratory - Princeton University