ASD

GO:0019935 cyclic-nucleotide-mediated signaling (154)

GeneInput weightStandardRank
GNAO1--4
CNR10.25129
ADCY2--175
GNAQ--189
SSTR2--251
RIMS2--282
ADCY10.251466
RAPGEF2--540
PRKACB--584
CRHR1--589
APLP1--591
NPY0.251592
HTR1E0.251695
GNAZ--856
DRD10.251899
RAPGEF40.251904
ADORA1--960
SOX9--1970
OPRK10.251996
CALCA--1013
NPY2R0.2511024
ADRB1--1057
DRD50.2511103
GNAL--1177
NPY1R0.2511190
GRIK30.2511247
GNAI3--1262
ADCYAP1R1--1273
FZD7--1357
FSHR--11398
ADRA2A0.2511399
HRH3--1428
GNAI1--1468
PTGER3--1587
GNAS--11842
ADCY9--1850
SPECC1L--1912
AGTR20.2511955
SSTR1--1959
PTHLH--11993
EPHA5--2077
OPRM10.2512212
GNA11--2281
HTR70.2512365
CALCR--2381
HTR5A0.2512606
ADCY8--2785
CHRM2--2799
ADCY6--2877
MCHR10.2512905
ADRB3--12953
LHCGR0.2513057
FZD3--3193
HTR1A0.2513315
TSHR--3382
GNA14--3634
CHRM50.2513694
DRD20.2513749
RXFP1--3767
MC2R--3795
GNAT3--3827
HTR1F--3836
MC4R0.2513850
HTR60.2514100
HTR4--4168
GHRHR--4237
FLNA--14285
ADCY5--4295
S1PR1--4301
P2RY1--4342
DRD30.2514349
CALCRL0.2514392
GRK5--4595
PTH1R--4648
P2RY12--4729
MTNR1A0.2514922
ADRA1B0.2514946
MC5R--4977
CCR3--5157
GCG--5190
NUDT4--5300
GPR3--5301
NPR3--5370
CHRM4--5408
GNAT2--5443
GLP2R--5519
CRHR2--5751
ADCY3--5755
GNAI2--5860
RXFP2--15887
GALR1--5908
OPRD10.2516030
OPRL10.2516271
MTNR1B0.2516286
XCR1--6470
GNA13--6683
S1PR3--6774
GCGR--16828
PTH--6947
DRD40.2517021
AVPR2--17031
GRM4--7321
GHRH--7478
HTR1D0.2517763
ADRA1D--7837
MC1R--17999
HTR1B0.2518092
MC3R0.2518188
GPR26--8197
ADORA2A0.2518408
AVPR1B0.2518546
PDE7A--8858
ADCY4--9091
VIPR10.2519277
GLP1R--9893
SSTR4--9920
GIPR--10369
HRH2--10518
RGS1--10535
UCN3--10665
PTGDR2--10914
PDZD3--11066
CNR20.25111649
LPAR3--11897
WASF2--12417
CORT--12689
AGT--113305
GNA12--14481
EIF4EBP2--14825
SSTR50.25114876
GALR2--14926
PTGER4--15180
ADM2--15255
FZD2--16930
SSTR3--18309
INSL3--119059
FZD6--19921
GNAT1--119999
FZD1--20775
GNA15--20926
GPR78--20984
ADM--21106
FPR1--21375
PTGIR0.25121564
CCR1--21851
SLC9A3R1--21898
S1PR4--22105
NDUFS4--122766
CCL2--23209
ADRB20.25123251
APOE0.25123516
CD36--23662
TBL3--24834
ADCY7--25408

Network

GO:0019935

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
GNAQguanine nucleotide binding protein (G protein), q polypeptide Entrez:2776  HGNC: 4390  HPRD: 02998 
SSTR2somatostatin receptor 2 Entrez:6752  HPRD: 01674  HGNC: 11331 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1cannabinoid receptor 1 (brain)
ADCY2adenylate cyclase 2 (brain)
GNAQguanine nucleotide binding protein (G protein), q polypeptide
SSTR2somatostatin receptor 2
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1CNR1cannabinoid receptor 1 (brain)
ADCY2ADCY2adenylate cyclase 2 (brain)
GNAQGNAQguanine nucleotide binding protein (G protein), q polypeptide
SSTR2SSTR2somatostatin receptor 2

Troyanskaya Laboratory - Princeton University