GO:0031281 positive regulation of cyclase activity (63)

GeneInput weightStandardRank
NTRK20.25151
ADCY2--175
GNAQ--189
ADCYAP1--230
NF10.251372
ADCY10.251466
CRHR1--589
DRD10.251899
CALCA--1013
ADRB1--1057
DRD50.2511103
GNAL--1177
ADCYAP1R1--1273
FSHR--11398
CAP2--1512
VIPR2--1823
GNAS--11842
ADCY9--1850
SPECC1L--1912
PTHLH--11993
HTR70.2512365
CALCR--2381
CAP1--2541
ADCY8--2785
ADCY6--2877
ADRB3--12953
LHCGR0.2513057
TSHR--3382
RXFP1--3767
EDNRA--13857
HTR4--4168
GHRHR--4237
ADCY5--4295
DRD30.2514349
CALCRL0.2514392
GPR3--5301
ADCY3--5755
RXFP2--15887
GALR1--5908
ACR--6002
GNA13--6683
ADORA3--6739
GCGR--16828
PTH--6947
AVPR2--17031
GHRH--7478
GPR26--8197
ADORA2A0.2518408
NTRK10.2518522
ADCY4--9091
GLP1R--9893
GIPR--10369
UCN3--10665
GALR2--14926
ADM2--15255
ADORA2B--19522
NOS3--20542
P2RY11--20669
GPR78--20984
SLC9A3R1--21898
S1PR4--22105
ADRB20.25123251
ADCY7--25408

Network

GO:0031281

Network
Enrichment
NameDescriptionExternal IDs
NTRK2neurotrophic tyrosine kinase, receptor, type 2 Entrez:4915  Ensembl: ENSG00000148053  HPRD: 02712  HGNC: 8032 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
GNAQguanine nucleotide binding protein (G protein), q polypeptide Entrez:2776  HGNC: 4390  HPRD: 02998 
ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary) Entrez:116  HGNC: 241  HPRD: 02369  Ensembl: ENSG00000141433 
NF1neurofibromin 1 Entrez:4763  HGNC: 7765  HPRD: 01203  Ensembl: ENSG00000196712 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK2neurotrophic tyrosine kinase, receptor, type 2
ADCY2adenylate cyclase 2 (brain)
GNAQguanine nucleotide binding protein (G protein), q polypeptide
ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)
NF1neurofibromin 1
Query geneGeneGene descriptionEdge score
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2
ADCY2ADCY2adenylate cyclase 2 (brain)
GNAQGNAQguanine nucleotide binding protein (G protein), q polypeptide
ADCYAP1ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)
NF1NF1neurofibromin 1