ASD

GO:0002762 negative regulation of myeloid leukocyte differentiation (25)

GeneInput weightStandardRank
SFRP1--387
TOB2--880
CALCA--1013
RUNX1--11449
CARTPT0.2511957
HOXA7--3411
RARA0.2513695
NME2--3712
LRRC17--3841
PRDM16--4345
INHA--4765
THOC5--4981
ADIPOQ0.2516032
IL4--6852
GPR55--8693
CTNNB10.519066
ZNF675--11676
TLR4--112795
NME1--113556
C1QC--15231
INHBA--16974
TLR3--22478
INPP5D--23776
NME1-NME2--25082
FSTL3--25154

Network

GO:0002762

Network
Enrichment
NameDescriptionExternal IDs
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
TOB2transducer of ERBB2, 2 Entrez:10766  HGNC: 11980  HPRD: 09583  Ensembl: ENSG00000183864 
CALCAcalcitonin-related polypeptide alpha Entrez:796  HGNC: 1437  HPRD: 00238  Ensembl: ENSG00000110680 
RUNX1runt-related transcription factor 1 Entrez:861  HPRD: 01043  Ensembl: ENSG00000159216  HGNC: 10471 
CARTPTCART prepropeptide Entrez:9607  HGNC: 24323  HPRD: 04006  Ensembl: ENSG00000164326 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SFRP1secreted frizzled-related protein 1
TOB2transducer of ERBB2, 2
CALCAcalcitonin-related polypeptide alpha
RUNX1runt-related transcription factor 1
CARTPTCART prepropeptide
Query geneGeneGene descriptionEdge score
SFRP1SFRP1secreted frizzled-related protein 1
TOB2TOB2transducer of ERBB2, 2
CALCACALCAcalcitonin-related polypeptide alpha
RUNX1RUNX1runt-related transcription factor 1
CARTPTCARTPTCART prepropeptide

Troyanskaya Laboratory - Princeton University