ASD

GO:0048863 stem cell differentiation (60)

GeneInput weightStandardRank
SOX2--1200
SOX4--250
APC0.251266
SFRP1--387
PAX2--653
ZCCHC11--737
DICER1--1762
JARID2--946
SOX9--1970
NR2E10.251977
BMPR1A--1140
ZHX2--1216
LDB2--1347
FZD7--1357
SOX10--11520
XRCC5--1550
VANGL2--1793
FGFR1--2262
SOX21--2559
FGFR3--12640
IGF10.2512793
SKI--2904
NODAL--13149
KLF10--3457
CDON--3487
PAX7--13577
KLF4--3609
CDX2--4071
NANOG--4083
TET1--4338
ESRRB0.2514453
FGF10--14532
WNT3--4613
PIWIL2--4828
FGF4--4938
NOG--15439
ZNF358--5591
OSR1--5691
HES10.2515912
NOTCH2--16664
LIN28A--7070
LIG4--17187
WNT7A--7312
HNF1B--19881
ASCL2--10237
ACE--10304
NANOS2--10402
LDB1--10693
VPS72--10808
RIF1--11422
TCF7L1--12273
FGF2--13150
SHH--118571
POU5F1--19704
FZD1--20775
TCL1A--21526
ERCC2--121804
LIF--22134
YAP1--22469
TPT1--25343

Network

GO:0048863

Network
Enrichment
NameDescriptionExternal IDs
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
APCadenomatous polyposis coli Entrez:324  HGNC: 583  HPRD: 01439  Ensembl: ENSG00000134982 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX2SRY (sex determining region Y)-box 2
SOX4SRY (sex determining region Y)-box 4
APCadenomatous polyposis coli
SFRP1secreted frizzled-related protein 1
PAX2paired box 2
Query geneGeneGene descriptionEdge score
SOX2SOX2SRY (sex determining region Y)-box 2
SOX4SOX4SRY (sex determining region Y)-box 4
APCAPCadenomatous polyposis coli
SFRP1SFRP1secreted frizzled-related protein 1
PAX2PAX2paired box 2

Troyanskaya Laboratory - Princeton University