ASD

GO:0051220 cytoplasmic sequestering of protein (17)

GeneInput weightStandardRank
YWHAB0.251107
G3BP2--610
MXI1--11763
PSMD10--2412
LATS1--2781
FLNA--14285
NFKBIA--5569
KEAP1--6103
GOPC--6764
IL10--19513
MDFI--13519
NFKBIE--19710
NFKBIL1--20431
TONSL--20639
TACC3--21671
NFKBIB--22875
FAF1--23304

Network

GO:0051220

Network
Enrichment
NameDescriptionExternal IDs
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
G3BP2GTPase activating protein (SH3 domain) binding protein 2 Entrez:9908  HPRD: 06570  HGNC: 30291  Ensembl: ENSG00000138757 
MXI1MAX interactor 1, dimerization protein Entrez:4601  HGNC: 7534  HPRD: 02486  Ensembl: ENSG00000119950 
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 Entrez:5716  HPRD: 04594  HGNC: 9555  Ensembl: ENSG00000101843 
LATS1large tumor suppressor kinase 1 Entrez:9113  HPRD: 09147  HGNC: 6514  Ensembl: ENSG00000131023 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
G3BP2GTPase activating protein (SH3 domain) binding protein 2
MXI1MAX interactor 1, dimerization protein
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
LATS1large tumor suppressor kinase 1
Query geneGeneGene descriptionEdge score
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
G3BP2G3BP2GTPase activating protein (SH3 domain) binding protein 2
MXI1MXI1MAX interactor 1, dimerization protein
PSMD10PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
LATS1LATS1large tumor suppressor kinase 1

Troyanskaya Laboratory - Princeton University