ASD

GO:0001708 cell fate specification (48)

GeneInput weightStandardRank
NTRK30.2516
SOX2--1200
ASCL1--413
POU4F1--475
PAX60.251544
OLIG2--619
PAX2--653
SOX9--1970
NKX2-2--1120
SOX6--1923
ISL1--1974
FOXA1--1990
FOXA2--2645
NOTCH1--12865
NODAL--13149
CDON--3487
ITGB1--3903
SOX17--4024
HOXA13--4036
NANOG--4083
HOXA11--4432
HOXD10--4534
NKX6-1--4665
NKX6-2--4791
HOXC10--5156
MNX1--5812
PRDM14--5965
EYA2--6194
GLI3--16261
SIX2--6306
TLX3--6462
FOXI1--16510
IHH--17160
GLI2--17307
GSX2--8581
MYL2--18834
CTNNB10.519066
LBX1--9134
FOXI2--9637
FOXA3--10333
ATOH1--11336
EVX1--15344
FOXI3--15933
PSEN1--18523
SHH--118571
POU5F1--19704
PSEN2--23095
TEAD4--25568

Network

GO:0001708

Network
Enrichment
NameDescriptionExternal IDs
NTRK3neurotrophic tyrosine kinase, receptor, type 3 Entrez:4916  Ensembl: ENSG00000140538  HPRD: 01870  HGNC: 8033 
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
POU4F1POU class 4 homeobox 1 Entrez:5457  Ensembl: ENSG00000152192  HGNC: 9218  HPRD: 03379 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK3neurotrophic tyrosine kinase, receptor, type 3
SOX2SRY (sex determining region Y)-box 2
ASCL1achaete-scute complex homolog 1 (Drosophila)
POU4F1POU class 4 homeobox 1
PAX6paired box 6
Query geneGeneGene descriptionEdge score
NTRK3NTRK3neurotrophic tyrosine kinase, receptor, type 3
SOX2SOX2SRY (sex determining region Y)-box 2
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
POU4F1POU4F1POU class 4 homeobox 1
PAX6PAX6paired box 6

Troyanskaya Laboratory - Princeton University