ASD

GO:0071695 anatomical structure maturation (26)

GeneInput weightStandardRank
CACNA1A--1270
GRIN1--294
PAX2--653
TGFB2--834
AKT10.2511020
FGFR3--12640
IGF10.2512793
NOTCH1--12865
WNT1--4383
BMP2--14855
PTGS20.2515085
PPARD--6562
TRPV10.2517162
GH1--7858
BARX2--8393
SPINK5--18777
ACVRL1--111656
LEP0.25111864
MREG--13587
PSEN1--18523
CDH5--19914
ERCC2--121804
LYL1--22065
THBS3--23018
PSEN2--23095
MMP2--25584

Network

GO:0071695

Network
Enrichment
NameDescriptionExternal IDs
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 Entrez:2902  HGNC: 4584  HPRD: 15926  Ensembl: ENSG00000176884 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
PAX2paired box 2
TGFB2transforming growth factor, beta 2
AKT1v-akt murine thymoma viral oncogene homolog 1
Query geneGeneGene descriptionEdge score
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
GRIN1GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
PAX2PAX2paired box 2
TGFB2TGFB2transforming growth factor, beta 2
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1

Troyanskaya Laboratory - Princeton University