ASD

GO:0001841 neural tube formation (57)

GeneInput weightStandardRank
SOX11--96
SOX4--250
LRP6--279
SFRP1--387
SALL1--506
PFN1--548
PAX2--653
LHX2--655
TSC10.251790
PTCH1--1972
MIB10.2511153
LMO4--1244
MAP3K7--1275
DLC1--1282
ENAH--1348
ZIC2--11609
VANGL2--1793
COBL0.2512536
TULP3--2770
SKI--2904
TFAP2A--12923
DEAF11.013084
NODAL--13149
FZD3--3193
TGIF1--13264
OPA1--3271
T--3286
WNT5A--3319
ALX1--4544
RGMA--4758
SFRP2--5252
CELSR1--6180
IFT122--16355
ZEB2--6361
BMP4--16499
DVL2--6546
GDF7--6682
IPMK--6705
TWIST1--16980
VASP--7880
KDM2B--8359
TSC20.2519351
SUFU--19372
SALL4--9929
BBS4--110131
FUZ--12978
PTK7--13643
IFT52--16599
SHH--118571
TEAD2--19466
FZD6--19921
ADM--21106
KAT2A--21262
BCL10--122368
IFT172--22658
CASP8--124587
LIAS--24813

Network

GO:0001841

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
SALL1sal-like 1 (Drosophila) Entrez:6299  HGNC: 10524  Ensembl: ENSG00000103449  HPRD: 03742 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
SOX4SRY (sex determining region Y)-box 4
LRP6low density lipoprotein receptor-related protein 6
SFRP1secreted frizzled-related protein 1
SALL1sal-like 1 (Drosophila)
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
SOX4SOX4SRY (sex determining region Y)-box 4
LRP6LRP6low density lipoprotein receptor-related protein 6
SFRP1SFRP1secreted frizzled-related protein 1
SALL1SALL1sal-like 1 (Drosophila)

Troyanskaya Laboratory - Princeton University