ASD

GO:0030838 positive regulation of actin filament polymerization (29)

GeneInput weightStandardRank
PFN2--551
ACTR3--803
RAC1--1617
ARPC2--1648
ARPC4--2880
NCK2--3077
ARF6--3317
MAP3K1--13381
DLG1--3822
MLST8--5028
JMY--5725
CCL11--9615
SCIN--9620
CDC42EP5--9805
WASH3P--10817
WASH2P--11022
RHOC--11655
NCK1--12890
WASH6P--13829
WASH1--15718
WASH4P--17760
CDC42EP2--19500
MTOR--21095
CCL21--21829
CCL24--21868
CCR7--22367
CCL26--22814
NCKAP1L--23771
BAIAP2L1--24041

Network

GO:0030838

Network
Enrichment
NameDescriptionExternal IDs
PFN2profilin 2 Entrez:5217  Ensembl: ENSG00000070087  HGNC: 8882  HPRD: 01451 
ACTR3ARP3 actin-related protein 3 homolog (yeast) Entrez:10096  HGNC: 170  Ensembl: ENSG00000115091  HPRD: 05024 
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Entrez:5879  Ensembl: ENSG00000136238  HPRD: 03627  HGNC: 9801 
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa Entrez:10109  HPRD: 10367  Ensembl: ENSG00000163466  HGNC: 705 
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa Entrez:10093  Ensembl: ENSG00000241553  HGNC: 707  HPRD: 10368 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PFN2profilin 2
ACTR3ARP3 actin-related protein 3 homolog (yeast)
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa
Query geneGeneGene descriptionEdge score
PFN2PFN2profilin 2
ACTR3ACTR3ARP3 actin-related protein 3 homolog (yeast)
RAC1RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
ARPC2ARPC2actin related protein 2/3 complex, subunit 2, 34kDa
ARPC4ARPC4actin related protein 2/3 complex, subunit 4, 20kDa

Troyanskaya Laboratory - Princeton University