ASD

GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity (10)

GeneInput weightStandardRank
PRKCI--568
ANK1--1555
VANGL2--1793
ERBB2IP--1926
MARK2--2280
PRICKLE2--13234
FOXF1--13518
ILK--7305
SYNE4--8828
PTK7--13643

Network

GO:0045197

Network
Enrichment
NameDescriptionExternal IDs
PRKCIprotein kinase C, iota Entrez:5584  HGNC: 9404  HPRD: 02105  Ensembl: ENSG00000163558 
ANK1ankyrin 1, erythrocytic Entrez:286  Ensembl: ENSG00000029534  HPRD: 01693  HGNC: 492 
VANGL2VANGL planar cell polarity protein 2 Entrez:57216  Ensembl: ENSG00000162738  HGNC: 15511  HPRD: 02758 
ERBB2IPerbb2 interacting protein Entrez:55914  HGNC: 15842  HPRD: 06090  Ensembl: ENSG00000112851 
MARK2MAP/microtubule affinity-regulating kinase 2 Entrez:2011  HGNC: 3332  Ensembl: ENSG00000072518  HPRD: 02753 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PRKCIprotein kinase C, iota
ANK1ankyrin 1, erythrocytic
VANGL2VANGL planar cell polarity protein 2
ERBB2IPerbb2 interacting protein
MARK2MAP/microtubule affinity-regulating kinase 2
Query geneGeneGene descriptionEdge score
PRKCIPRKCIprotein kinase C, iota
ANK1ANK1ankyrin 1, erythrocytic
VANGL2VANGL2VANGL planar cell polarity protein 2
ERBB2IPERBB2IPerbb2 interacting protein
MARK2MARK2MAP/microtubule affinity-regulating kinase 2

Troyanskaya Laboratory - Princeton University