ASD

GO:0030510 regulation of BMP signaling pathway (50)

GeneInput weightStandardRank
SOX11--96
TRIM33--1147
BMPR2--1281
SFRP1--387
CHRD--941
ACVR2A--965
PCSK6--1035
HIPK2--1051
SMAD7--1192
LEMD3--12084
SMAD6--2305
NOTCH1--12865
SKI--2904
SOSTDC1--3003
SMURF1--3060
WNT5A--3319
BMPER--3497
GREM1--3867
HOXA13--4036
RGMA--4758
HES5--4919
SFRP2--5252
NOG--15439
HES10.2515912
FOXD2--6176
SOST--6885
CER1--6956
ILK--7305
FOXD4L1--7836
FOXD1--7884
GPC3--18430
VWC2--8879
FOXD4L4--9599
GATA6--110828
FBN1--110976
DKK1--11567
FOXD4--11635
ACVRL1--111656
FBXL15--12126
GATA4--112466
SKOR1--12870
FOXD4L5--13951
FOXD4L2--16505
FOXD4L6--19555
FZD1--20775
CYR61--22574
ENG--124746
TWSG1--24840
FSTL3--25154
CAV1--125381

Network

GO:0030510

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
TRIM33tripartite motif containing 33 Entrez:51592  HPRD: 10423  HGNC: 16290  Ensembl: ENSG00000197323 
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
CHRDchordin Entrez:8646  Ensembl: ENSG00000090539  HGNC: 1949  HPRD: 04592 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
TRIM33tripartite motif containing 33
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
SFRP1secreted frizzled-related protein 1
CHRDchordin
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
TRIM33TRIM33tripartite motif containing 33
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
SFRP1SFRP1secreted frizzled-related protein 1
CHRDCHRDchordin

Troyanskaya Laboratory - Princeton University