ASD

GO:0030032 lamellipodium assembly (18)

GeneInput weightStandardRank
ARHGEF4--265
RAC1--1617
CDH13--1692
CAPZB--2179
VAV2--2850
VAV3--2908
NCK2--3077
ARFIP2--3261
SH2B1--3387
CCDC88A--3536
CYFIP1--6339
LRRC16A--7272
FGD4--17457
SPATA13--9353
WASF2--12417
AJUBA--18146
VCL--120732
NUP85--25247

Network

GO:0030032

Network
Enrichment
NameDescriptionExternal IDs
ARHGEF4Rho guanine nucleotide exchange factor (GEF) 4 Entrez:50649  Ensembl: ENSG00000136002  HGNC: 684  HPRD: 05559 
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Entrez:5879  Ensembl: ENSG00000136238  HPRD: 03627  HGNC: 9801 
CDH13cadherin 13 Entrez:1012  Ensembl: ENSG00000140945  HGNC: 1753  HPRD: 03219 
CAPZBcapping protein (actin filament) muscle Z-line, beta Entrez:832  HGNC: 1491  HPRD: 11872  Ensembl: ENSG00000077549 
VAV2vav 2 guanine nucleotide exchange factor Entrez:7410  HGNC: 12658  HPRD: 02694  Ensembl: ENSG00000160293 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ARHGEF4Rho guanine nucleotide exchange factor (GEF) 4
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
CDH13cadherin 13
CAPZBcapping protein (actin filament) muscle Z-line, beta
VAV2vav 2 guanine nucleotide exchange factor
Query geneGeneGene descriptionEdge score
ARHGEF4ARHGEF4Rho guanine nucleotide exchange factor (GEF) 4
RAC1RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
CDH13CDH13cadherin 13
CAPZBCAPZBcapping protein (actin filament) muscle Z-line, beta
VAV2VAV2vav 2 guanine nucleotide exchange factor

Troyanskaya Laboratory - Princeton University