ASD

GO:0000187 activation of MAPK activity (111)

GeneInput weightStandardRank
MAP3K9--462
SPAG9--558
MADD--759
TAB2--785
MAP2K10.251907
GNG3--927
GRM10.251975
MAPK1--1128
GAB1--1198
MAP3K5--1220
MAP2K20.2511240
MAP3K7--1275
ADRA2A0.2511399
CHRNA70.511837
TGFA--1873
MAPK11--1962
PKN1--1967
MAPK8IP3--2274
SOD1--12702
MAP4K5--2894
MAP3K10--2968
MAP3K2--3184
WNT5A--3319
MAP3K1--13381
DAB2IP--3482
TAB3--3641
MAPKAPK2--3870
MAPK14--3975
PDE6H--4126
LPAR1--4170
AXIN1--14419
FGF10--14532
PROK2--14655
HGF0.2515313
CXCR4--5414
PRDX2--5497
MAP2K7--5837
INSR--15872
PLA2G1B--6059
TDGF1--6132
MAPK30.2516426
LPAR2--6450
UBC--6756
PLCE1--6929
DRD40.2517021
WNT7B--7113
FRS2--7173
TAB1--7218
WNT7A--7312
GRM4--7321
FGD4--17457
MET1.018002
DAXX--8508
ADRA2C--8551
PROK1--9002
GHRL0.2519242
C1QTNF2--10034
SHC1--10045
GHR--110098
ADRA2B--10119
MAP2K6--10478
IL1B--110818
TRAF6--11055
PIK3CB--11542
LPAR3--11897
CD81--112160
EPGN--12503
TLR4--112795
MAP3K11--12938
TGFB3--113097
FGF2--13150
MDFI--13519
MAP2K3--13704
CCL19--14578
IRAK2--15024
TNF0.25115243
ITGA1--15500
TP73--18810
IQGAP3--19438
UBB--19448
ADORA2B--19522
BIRC7--19826
PTPLAD1--20272
PDE6G--120364
MAP4K2--20522
RIPK2--20830
C5AR1--21363
FPR1--21375
EFNA1--21477
NOD2--121514
IRAK1--21640
MDFIC--21692
ADAM8--21797
C5--122004
MAP4K1--22336
DBNL--22402
S1PR2--22592
RIPK1--22681
PRKAA1--22917
MUL1--22953
NOD1--23388
IKBKG--123539
AVPI1--23843
SYK--23906
CD74--24030
MAPKAPK3--24170
MAP3K6--24220
RPS27A--24381
UBA52--24384
THBS1--24444
CDK1--25053

Network

GO:0000187

Network
Enrichment
NameDescriptionExternal IDs
MAP3K9mitogen-activated protein kinase kinase kinase 9 Entrez:4293  Ensembl: ENSG00000006432  HGNC: 6861  HPRD: 15965 
SPAG9sperm associated antigen 9 Entrez:9043  HPRD: 10398  HGNC: 14524  Ensembl: ENSG00000008294 
MADDMAP-kinase activating death domain Entrez:8567  HGNC: 6766  Ensembl: ENSG00000110514  HPRD: 04664 
TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 2 Entrez:23118  HGNC: 17075  Ensembl: ENSG00000055208  HPRD: 05483 
MAP2K1mitogen-activated protein kinase kinase 1 Entrez:5604  HGNC: 6840  HPRD: 01469 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAP3K9mitogen-activated protein kinase kinase kinase 9
SPAG9sperm associated antigen 9
MADDMAP-kinase activating death domain
TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 2
MAP2K1mitogen-activated protein kinase kinase 1
Query geneGeneGene descriptionEdge score
MAP3K9MAP3K9mitogen-activated protein kinase kinase kinase 9
SPAG9SPAG9sperm associated antigen 9
MADDMADDMAP-kinase activating death domain
TAB2TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 2
MAP2K1MAP2K1mitogen-activated protein kinase kinase 1

Troyanskaya Laboratory - Princeton University