ASD

GO:0010594 regulation of endothelial cell migration (51)

GeneInput weightStandardRank
BMPR2--1281
NF10.251372
SLIT2--659
PRKD1--909
NR2E10.251977
PROX1--997
AKT10.2511020
PRKCA--1027
AMOT--1325
HDAC5--1950
AGTR20.2511955
PRKD2--2228
GATA3--2376
NR2F2--2941
VASH10.2513148
HDAC9--3228
WNT5A--3319
BMPER--3497
VEGFA0.2514087
ANGPT1--4182
PLCG1--4744
PTPRM--4769
KDR0.2514854
PTGS20.2515085
BMP10--5102
KRIT1--6163
DLL4--6365
BMP4--16499
EDN1--9540
FOXC2--10175
ANGPT4--10249
ANGPT2--10581
PPAP2B--10628
APOH--11562
ACVRL1--111656
ITGB30.5111817
VEGFC--12850
FGF2--13150
AAMP--13187
AGT--113305
SCARB1--13530
GDF2--14603
HDAC7--14702
ALOX12--14851
EPHA2--119467
TGFB10.25120135
PDGFB--21071
SRPX2--21503
ANXA3--22980
APOE0.25123516
THBS1--24444

Network

GO:0010594

Network
Enrichment
NameDescriptionExternal IDs
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
NF1neurofibromin 1 Entrez:4763  HGNC: 7765  HPRD: 01203  Ensembl: ENSG00000196712 
SLIT2slit homolog 2 (Drosophila) Entrez:9353  Ensembl: ENSG00000145147  HPRD: 04776  HGNC: 11086 
PRKD1protein kinase D1 Entrez:5587  Ensembl: ENSG00000184304  HPRD: 05668  HGNC: 9407 
NR2E1nuclear receptor subfamily 2, group E, member 1 Entrez:7101  Ensembl: ENSG00000112333  HGNC: 7973  HPRD: 07230 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
NF1neurofibromin 1
SLIT2slit homolog 2 (Drosophila)
PRKD1protein kinase D1
NR2E1nuclear receptor subfamily 2, group E, member 1
Query geneGeneGene descriptionEdge score
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
NF1NF1neurofibromin 1
SLIT2SLIT2slit homolog 2 (Drosophila)
PRKD1PRKD1protein kinase D1
NR2E1NR2E1nuclear receptor subfamily 2, group E, member 1

Troyanskaya Laboratory - Princeton University