ASD

GO:0048701 embryonic cranial skeleton morphogenesis (30)

GeneInput weightStandardRank
NIPBL--17
SMAD3--823
GNAS--11842
PRRX1--2125
DLX20.2512357
LHX1--2560
SMAD2--2694
TULP3--2770
TFAP2A--12923
NODAL--13149
SIX4--3738
HOXA2--4273
NDST1--5114
TBX15--5222
TBX10.2515772
SIX2--6306
BMP4--16499
GAS1--6937
TWIST1--16980
TGFBR1--17268
WNT9B--8217
CHST11--9003
RDH10--9300
FOXC2--10175
TGFBR2--110407
SMO0.25110504
SIX1--112393
TGFB3--113097
TWIST2--15321
PRRX2--23936

Network

GO:0048701

Network
Enrichment
NameDescriptionExternal IDs
NIPBLNipped-B homolog (Drosophila) Entrez:25836  HPRD: 10560  HGNC: 28862  Ensembl: ENSG00000164190 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
GNASGNAS complex locus Entrez:2778  HGNC: 4392  HPRD: 00761  Ensembl: ENSG00000087460 
PRRX1paired related homeobox 1 Entrez:5396  HPRD: 01337  HGNC: 9142  Ensembl: ENSG00000116132 
DLX2distal-less homeobox 2 Entrez:1746  Ensembl: ENSG00000115844  HGNC: 2915  HPRD: 00527 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NIPBLNipped-B homolog (Drosophila)
SMAD3SMAD family member 3
GNASGNAS complex locus
PRRX1paired related homeobox 1
DLX2distal-less homeobox 2
Query geneGeneGene descriptionEdge score
NIPBLNIPBLNipped-B homolog (Drosophila)
SMAD3SMAD3SMAD family member 3
GNASGNASGNAS complex locus
PRRX1PRRX1paired related homeobox 1
DLX2DLX2distal-less homeobox 2

Troyanskaya Laboratory - Princeton University