ASD

GO:0007219 Notch signaling pathway (55)

GeneInput weightStandardRank
SPEN--9
EFNB2--148
CNTN1--299
ASCL1--413
DLL3--1847
MAML1--852
NRG10.251936
MIB10.2511153
HOXD3--1195
HEY1--1280
APP--1515
RBPJ--1595
JAG2--1612
DTX3--1677
JAG1--11704
DLL1--2053
DNER--2126
CNTN6--2198
DTX4--2332
NOTCH1--12865
HEY2--3174
NEUROD4--4242
RBM15--4247
FURIN--4605
MAML2--4659
BMP10--5102
ADAM17--5323
NOTCH2NL--5637
HES10.2515912
DLL4--6365
MAML3--6646
NOTCH2--16664
FOXC2--10175
SEL1L--10588
HES7--110974
HEYL--12571
APH1A0.5113440
FOXC1--113793
DTX2--17265
PSEN1--18523
NOTCH4--19230
MIB2--19990
FOXS1--20143
PSENEN--120566
POFUT1--20616
ADAM10--20986
NCSTN--120988
NOTCH3--22114
MESP2--122723
PSEN2--23095
CFD--23364
NKAP--23839
APH1B--24417
NLE1--25368
WDR12--25789

Network

GO:0007219

Network
Enrichment
NameDescriptionExternal IDs
SPENspen homolog, transcriptional regulator (Drosophila) Entrez:23013  HPRD: 10230  Ensembl: ENSG00000065526  HGNC: 17575 
EFNB2ephrin-B2 Entrez:1948  Ensembl: ENSG00000125266  HPRD: 02754  HGNC: 3227 
CNTN1contactin 1 Entrez:1272  HGNC: 2171  HPRD: 07189  Ensembl: ENSG00000018236 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
DLL3delta-like 3 (Drosophila) Entrez:10683  Ensembl: ENSG00000090932  HGNC: 2909  HPRD: 04140 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SPENspen homolog, transcriptional regulator (Drosophila)
EFNB2ephrin-B2
CNTN1contactin 1
ASCL1achaete-scute complex homolog 1 (Drosophila)
DLL3delta-like 3 (Drosophila)
Query geneGeneGene descriptionEdge score
SPENSPENspen homolog, transcriptional regulator (Drosophila)
EFNB2EFNB2ephrin-B2
CNTN1CNTN1contactin 1
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
DLL3DLL3delta-like 3 (Drosophila)

Troyanskaya Laboratory - Princeton University