ASD

GO:0030177 positive regulation of Wnt receptor signaling pathway (54)

GeneInput weightStandardRank
UBR5--193
USP34--231
FGFR2--1237
SOX4--250
FGF9--262
LRP6--279
SFRP1--387
SALL1--506
CSNK1D--699
MACF1--715
CSNK1E0.251752
SMAD3--823
EDA--1925
DISC10.511238
TNKS--1414
WNT10B--1517
WNT2B--1673
PPM1A--2070
WNT20.2512299
DKK2--2331
FGFR3--12640
DLX5--2706
SKI--2904
ZRANB1--3481
DIXDC1--3734
CAPRIN2--4284
TNKS2--4385
MBD2--4518
FGF10--14532
RSPO2--4631
WNT3A--4747
SFRP2--5252
ZEB2--6361
RSPO1--7229
ILK--7305
SFRP4--7310
WNT7A--7312
RNF146--7910
GPC3--18430
BAMBI--8550
NRARP--14597
WLS--15707
SHH--118571
DVL1--18924
TLR2--119246
HHEX--19523
NFKB1--20281
JUP--120291
TRPM4--20948
WNT4--21809
YAP1--22469
COL1A1--124140
DAB2--25338
CAV1--125381

Network

GO:0030177

Network
Enrichment
NameDescriptionExternal IDs
UBR5ubiquitin protein ligase E3 component n-recognin 5 Entrez:51366  HPRD: 06436  Ensembl: ENSG00000104517  HGNC: 16806 
USP34ubiquitin specific peptidase 34 Entrez:9736  HGNC: 20066  HPRD: 11665  Ensembl: ENSG00000115464 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
FGF9fibroblast growth factor 9 Entrez:2254  HPRD: 02951  HGNC: 3687  Ensembl: ENSG00000102678 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
UBR5ubiquitin protein ligase E3 component n-recognin 5
USP34ubiquitin specific peptidase 34
FGFR2fibroblast growth factor receptor 2
SOX4SRY (sex determining region Y)-box 4
FGF9fibroblast growth factor 9
Query geneGeneGene descriptionEdge score
UBR5UBR5ubiquitin protein ligase E3 component n-recognin 5
USP34USP34ubiquitin specific peptidase 34
FGFR2FGFR2fibroblast growth factor receptor 2
SOX4SOX4SRY (sex determining region Y)-box 4
FGF9FGF9fibroblast growth factor 9

Troyanskaya Laboratory - Princeton University