ASD

GO:0006939 smooth muscle contraction (32)

GeneInput weightStandardRank
KCNMA10.251191
SSTR2--251
PDE4D--348
DRD10.251899
EDN3--11577
ADRA1A--1858
EDNRB--12042
FKBP1B--2346
DRD20.2513749
DLG1--3822
TSHZ3--3848
EDNRA--13857
GDNF--14658
CNN3--6611
KNG1--6802
HTR2B--6992
TRPV10.2517162
HTR1D0.2517763
EDN1--9540
BDKRB2--10150
TACR1--11618
MYL7--12219
AGT--113305
GAL--13897
ACTA2--114097
EDN2--18677
P2RX3--18725
NMUR1--19043
CHRNB20.25120216
SMTN--22560
MYH11--123442
TPCN2--23548

Network

GO:0006939

Network
Enrichment
NameDescriptionExternal IDs
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1 Entrez:3778  Ensembl: ENSG00000156113  HGNC: 6284  HPRD: 15967 
SSTR2somatostatin receptor 2 Entrez:6752  HPRD: 01674  HGNC: 11331 
PDE4Dphosphodiesterase 4D, cAMP-specific Entrez:5144  HPRD: 02530  HGNC: 8783  Ensembl: ENSG00000113448 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
EDN3endothelin 3 Entrez:1908  HGNC: 3178  Ensembl: ENSG00000124205  HPRD: 00570 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1
SSTR2somatostatin receptor 2
PDE4Dphosphodiesterase 4D, cAMP-specific
DRD1dopamine receptor D1
EDN3endothelin 3
Query geneGeneGene descriptionEdge score
KCNMA1KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1
SSTR2SSTR2somatostatin receptor 2
PDE4DPDE4Dphosphodiesterase 4D, cAMP-specific
DRD1DRD1dopamine receptor D1
EDN3EDN3endothelin 3

Troyanskaya Laboratory - Princeton University