ASD

GO:0030835 negative regulation of actin filament depolymerization (25)

GeneInput weightStandardRank
SHROOM2--937
SPTAN1--11287
DMTN--1465
SPTBN4--1647
SPTBN2--11935
CAPZB--2179
ADD2--2388
ADD1--12876
SPTB--3478
SPTBN1--3627
CAPZA2--4483
RDX--14697
CAPZA1--4983
SPTBN5--5319
SPTA1--16958
AVIL--7943
CAPZA3--8396
SCIN--9620
CAPG--20663
VIL10.5122243
VILL--22283
TWF2--23010
GSN--124007
TRIOBP--124113
LIMA1--24553

Network

GO:0030835

Network
Enrichment
NameDescriptionExternal IDs
SHROOM2shroom family member 2 Entrez:357  Ensembl: ENSG00000146950  HGNC: 630  HPRD: 02113 
SPTAN1spectrin, alpha, non-erythrocytic 1 Entrez:6709  HGNC: 11273  Ensembl: ENSG00000197694  HPRD: 01684 
DMTNdematin actin binding protein Entrez:2039  HPRD: 00506  Ensembl: ENSG00000158856  HGNC: 3382 
SPTBN4spectrin, beta, non-erythrocytic 4 Entrez:57731  HPRD: 09372  HGNC: 14896  Ensembl: ENSG00000160460 
SPTBN2spectrin, beta, non-erythrocytic 2 Entrez:6712  HGNC: 11276  Ensembl: ENSG00000173898  HPRD: 05404 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SHROOM2shroom family member 2
SPTAN1spectrin, alpha, non-erythrocytic 1
DMTNdematin actin binding protein
SPTBN4spectrin, beta, non-erythrocytic 4
SPTBN2spectrin, beta, non-erythrocytic 2
Query geneGeneGene descriptionEdge score
SHROOM2SHROOM2shroom family member 2
SPTAN1SPTAN1spectrin, alpha, non-erythrocytic 1
DMTNDMTNdematin actin binding protein
SPTBN4SPTBN4spectrin, beta, non-erythrocytic 4
SPTBN2SPTBN2spectrin, beta, non-erythrocytic 2

Troyanskaya Laboratory - Princeton University