ASD

GO:0032874 positive regulation of stress-activated MAPK cascade (14)

GeneInput weightStandardRank
MAPK8IP2--418
TGFB2--834
SEMA4C--1304
TAOK1--1336
TAOK20.2511633
MID1--2259
TAOK3--3466
IL1A--4651
IL1B--110818
IL26--11645
RIPK2--20830
NOD2--121514
NOD1--23388
CARD9--123577

Network

GO:0032874

Network
Enrichment
NameDescriptionExternal IDs
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 Entrez:23542  HPRD: 09674  Ensembl: ENSG00000008735  HGNC: 6883 
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
SEMA4Csema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C Entrez:54910  Ensembl: ENSG00000168758  HGNC: 10731  HPRD: 07257 
TAOK1TAO kinase 1 Entrez:57551  HGNC: 29259  Ensembl: ENSG00000160551  HPRD: 15467 
TAOK2TAO kinase 2 Entrez:9344  HGNC: 16835  Ensembl: ENSG00000149930  HPRD: 18147 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
TGFB2transforming growth factor, beta 2
SEMA4Csema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
TAOK1TAO kinase 1
TAOK2TAO kinase 2
Query geneGeneGene descriptionEdge score
MAPK8IP2MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
TGFB2TGFB2transforming growth factor, beta 2
SEMA4CSEMA4Csema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
TAOK1TAOK1TAO kinase 1
TAOK2TAOK2TAO kinase 2

Troyanskaya Laboratory - Princeton University