ASD

GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (13)

GeneInput weightStandardRank
FBXW7--198
CUL1--478
FBXW11--859
RBX1--1044
FBXL3--3648
SKP1--5249
FBXL15--12126
FBXO31--17598
FBXO2--18983
FBXO4--20319
FBXL5--22878
FBXO6--23542
CCNF--25571

Network

GO:0031146

Network
Enrichment
NameDescriptionExternal IDs
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
CUL1cullin 1 Entrez:8454  HGNC: 2551  HPRD: 04389  Ensembl: ENSG00000055130 
FBXW11F-box and WD repeat domain containing 11 Entrez:23291  Ensembl: ENSG00000072803  HPRD: 07294  HGNC: 13607 
RBX1ring-box 1, E3 ubiquitin protein ligase Entrez:9978  HPRD: 06794  HGNC: 9928 
FBXL3F-box and leucine-rich repeat protein 3 Entrez:26224  HPRD: 05737  HGNC: 13599  Ensembl: ENSG00000005812 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
CUL1cullin 1
FBXW11F-box and WD repeat domain containing 11
RBX1ring-box 1, E3 ubiquitin protein ligase
FBXL3F-box and leucine-rich repeat protein 3
Query geneGeneGene descriptionEdge score
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
CUL1CUL1cullin 1
FBXW11FBXW11F-box and WD repeat domain containing 11
RBX1RBX1ring-box 1, E3 ubiquitin protein ligase
FBXL3FBXL3F-box and leucine-rich repeat protein 3

Troyanskaya Laboratory - Princeton University