ASD

GO:0043523 regulation of neuron apoptosis (133)

GeneInput weightStandardRank
SET--31
ADNP1.0171
GABRA50.251161
SRPK2--171
GRIK20.51232
CACNA1A--1270
GRIN1--294
NF10.251372
UBE2M--381
ASCL1--413
GPI--1423
POU4F1--475
NR3C1--496
JUN--511
CRH--563
CDK5R1--586
CRHR1--589
SNCA--1667
TOX3--765
BDNF0.251791
TGFB2--834
EPHA7--837
NR4A3--1963
NR4A20.251992
PCSK6--1035
HIPK2--1051
ERBB3--1350
GRIK5--1396
SNCB--11511
GABRB2--1571
HRK--1660
CNTFR--1675
ITSN1--1789
ESR10.2511791
TGFA--1873
PPARGC1A--1909
SPECC1L--1912
UBE2V2--1939
ISL1--1974
RASA1--1983
TYRO3--2083
RHOA--2292
AGAP2--2378
DLX10.2512400
ATP7A--12483
BCL20.2512485
SOD1--12702
CITED1--3064
CDK50.2513194
GRID20.2513225
NTF30.2513232
PARK7--13322
BCL2L11--3469
ATM--13622
SIX4--3738
MUSK--4006
ROCK1--4378
NDNF--4408
RILPL1--4455
FURIN--4605
GDNF--14658
PTPRF--5040
HRAS0.2515086
FOXB1--5360
FASLG--15523
KCNIP3--5600
BARHL1--5649
CNTF--5784
MAP2K7--5837
AGRN0.2516010
NGF0.2516229
MSH2--16311
BCL2L1--6563
CRLF1--7152
LIG4--17187
ILK--7305
GRM4--7321
PMAIP1--7385
KDM2B--8359
ADORA2A0.2518408
CASP2--9480
BAX--9833
GLP1R--9893
GHR--110098
UCN--10358
CLN3--110442
XRCC2--10672
PCSK9--10760
BRAF--111149
GPX10.25111644
RHOC--11655
VEGFB--11980
GCLC--12360
SIX1--112393
NMNAT3--12461
IL6--112695
WFS10.25112793
MAP3K11--12938
TGFB3--113097
AGT--113305
NRBP2--13435
AKT1S1--13569
PPT1--113834
TNF0.25115243
ITGA1--15500
TP530.25118277
PSEN1--18523
TP73--18810
F2R--20036
PRDX3--20199
EPO--20282
RAPSN--20521
ABCC1--21066
CLCF1--21194
DHCR24--21358
ADAM8--21797
NMNAT1--22515
TP63--122528
SOD2--22687
MDK--22733
AARS--22782
NCF2--122977
CCL5--23042
CASP6--23087
ALKBH1--23309
HMOX1--23938
IL18--24018
AXL--24522
LGMN--24625
GCLM--24915
CASP7--25028
XRCC4--25256
NQO1--25542

Network

GO:0043523

Network
Enrichment
NameDescriptionExternal IDs
SETSET nuclear oncogene Entrez:6418  HGNC: 10760  HPRD: 09023  Ensembl: ENSG00000119335 
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  Ensembl: ENSG00000101126  HPRD: 09793  HGNC: 15766 
GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 5 Entrez:2558  Ensembl: ENSG00000186297  HPRD: 08840  HGNC: 4079 
SRPK2SRSF protein kinase 2 Entrez:6733  HPRD: 04280  Ensembl: ENSG00000135250  HGNC: 11306 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SETSET nuclear oncogene
ADNPactivity-dependent neuroprotector homeobox
GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 5
SRPK2SRSF protein kinase 2
GRIK2glutamate receptor, ionotropic, kainate 2
Query geneGeneGene descriptionEdge score
SETSETSET nuclear oncogene
ADNPADNPactivity-dependent neuroprotector homeobox
GABRA5GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 5
SRPK2SRPK2SRSF protein kinase 2
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2

Troyanskaya Laboratory - Princeton University