ASD

GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway (47)

GeneInput weightStandardRank
ADCY2--175
GNAQ--189
ADCY10.251466
CRHR1--589
DRD10.251899
CALCA--1013
ADRB1--1057
DRD50.2511103
GNAL--1177
FSHR--11398
GNAS--11842
ADCY9--1850
SPECC1L--1912
PTHLH--11993
HTR70.2512365
CALCR--2381
ADCY8--2785
ADCY6--2877
ADRB3--12953
TSHR--3382
RXFP1--3767
HTR4--4168
GHRHR--4237
ADCY5--4295
DRD30.2514349
CALCRL0.2514392
GPR3--5301
ADCY3--5755
RXFP2--15887
GALR1--5908
GNA13--6683
GCGR--16828
PTH--6947
GHRH--7478
GPR26--8197
ADORA2A0.2518408
ADCY4--9091
GLP1R--9893
GIPR--10369
UCN3--10665
GALR2--14926
ADM2--15255
GPR78--20984
SLC9A3R1--21898
S1PR4--22105
ADRB20.25123251
ADCY7--25408

Network

GO:0007189

Network
Enrichment
NameDescriptionExternal IDs
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
GNAQguanine nucleotide binding protein (G protein), q polypeptide Entrez:2776  HGNC: 4390  HPRD: 02998 
ADCY1adenylate cyclase 1 (brain) Entrez:107  HGNC: 232  HPRD: 00053  Ensembl: ENSG00000164742 
CRHR1corticotropin releasing hormone receptor 1 Entrez:1394  Ensembl: ENSG00000120088  HGNC: 2357  HPRD: 08830 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ADCY2adenylate cyclase 2 (brain)
GNAQguanine nucleotide binding protein (G protein), q polypeptide
ADCY1adenylate cyclase 1 (brain)
CRHR1corticotropin releasing hormone receptor 1
DRD1dopamine receptor D1
Query geneGeneGene descriptionEdge score
ADCY2ADCY2adenylate cyclase 2 (brain)
GNAQGNAQguanine nucleotide binding protein (G protein), q polypeptide
ADCY1ADCY1adenylate cyclase 1 (brain)
CRHR1CRHR1corticotropin releasing hormone receptor 1
DRD1DRD1dopamine receptor D1

Troyanskaya Laboratory - Princeton University