ASD

GO:0031570 DNA integrity checkpoint (126)

GeneInput weightStandardRank
PSMA1--58
PSMD14--104
PSMA4--166
PSMB3--234
SOX4--250
PSMA5--284
PSMD8--371
PSMA3--460
PSMB1--501
DGKZ--547
PPP2R5C--555
FOXN3--647
PSMC6--679
PSMD6--688
PSMB7--745
PSME4--787
PSMC2--815
PSMD11--967
PSMB4--1091
CLOCK0.2511134
CDKN1B--1162
PSMD1--1168
PSMA7--1174
PSMC4--1269
PSMC1--1296
TAOK1--1336
PSMA6--1510
PSMD12--1573
PSMB6--1607
TAOK20.2511633
PSMD2--1706
PSMC5--1897
PSMD3--2008
PSMD4--2087
CDC14B--2176
PSMC3--2240
PSMD10--2412
PSMD7--2481
PSMA2--2699
FZR1--2920
PSMD13--3051
NEK11--3141
TAOK3--3466
ATM--13622
MAPK14--3975
GML--4230
TIPRL--4308
NAE1--4421
BRSK1--5103
MSH2--16311
PCBP4--6634
MDM2--6675
UIMC1--6729
UBC--6756
CDKN1A--7714
CCND1--17970
RPA4--8552
H2AFX--8720
FOXO4--9362
BABAM1--9983
RFWD2--10076
PSMA8--10087
RBM38--11401
PSMB2--11986
PSMB11--12480
RAD9A--12557
MDC1--13132
PSMD9--13911
STRA8--14143
PSME2--14327
USP28--15068
PLK5--15898
NBN--116066
FBXO31--17598
TP530.25118277
TP73--18810
UBB--19448
BRE--19475
HINFP--19490
PSMD5--19823
BRCC3--20674
PSME1--21072
CLSPN--21302
PSMB9--21373
PSMB10--21853
PSMB8--22146
PSME3--22162
BRIP1--122269
PSMF1--22424
TP63--122528
RAD1--22725
HUS1--22873
CEP63--22973
FAM175A--22994
ATRIP--23073
XPC--123150
RAD17--23212
INTS7--23232
TICRR--23302
FBXO6--23542
CCNG1--23565
POLA1--23566
RFWD3--23570
RHNO1--23811
ATR--123866
GTSE1--24085
RPS27A--24381
UBA52--24384
TRIAP1--24476
BRCA1--124573
CHEK2--124807
CDK1--25053
RINT1--25118
RPS27L--25183
DTL--25229
PSMB5--25250
PML--25277
CDT1--25291
CDK2--25445
TIPIN--25538
CDC45--25728
CCNA2--25751
PLK1--25783
BLM--125798
CHEK1--25816
CDC6--25819

Network

GO:0031570

Network
Enrichment
NameDescriptionExternal IDs
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4 Entrez:5685  Ensembl: ENSG00000041357  HPRD: 10168  HGNC: 9533 
PSMB3proteasome (prosome, macropain) subunit, beta type, 3 Entrez:5691  HPRD: 03709  Ensembl: ENSG00000108294  HGNC: 9540 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMB3proteasome (prosome, macropain) subunit, beta type, 3
SOX4SRY (sex determining region Y)-box 4
Query geneGeneGene descriptionEdge score
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMA4PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMB3PSMB3proteasome (prosome, macropain) subunit, beta type, 3
SOX4SOX4SRY (sex determining region Y)-box 4

Troyanskaya Laboratory - Princeton University