ASD

GO:0017156 calcium ion-dependent exocytosis (26)

GeneInput weightStandardRank
VAMP2--33
RIMS30.251241
RIMS2--282
STX1A0.251512
GLRB--515
RIMS10.51777
RAPGEF40.251904
TRIM36--1781
GLRA1--2965
TNP2--3500
SYT6--3550
PKDREJ--4603
ACR--6002
AKAP3--6566
SDF4--6703
PLCD4--8160
SCIN--9620
CRCP--10705
SYT8--13124
ARHGAP17--13491
ZP4--14747
PCSK4--15108
STX2--19379
ROPN1B--19629
VAMP7--21789
VAMP3--24000

Network

GO:0017156

Network
Enrichment
NameDescriptionExternal IDs
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2) Entrez:6844  HGNC: 12643  HPRD: 01717  Ensembl: ENSG00000220205 
RIMS3regulating synaptic membrane exocytosis 3 Entrez:9783  HGNC: 21292  HPRD: 17976  Ensembl: ENSG00000117016 
RIMS2regulating synaptic membrane exocytosis 2 Entrez:9699  HGNC: 17283  HPRD: 09436 
STX1Asyntaxin 1A (brain) Entrez:6804  Ensembl: ENSG00000106089  HGNC: 11433  HPRD: 01721 
GLRBglycine receptor, beta Entrez:2743  HGNC: 4329  Ensembl: ENSG00000109738  HPRD: 11751 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
RIMS3regulating synaptic membrane exocytosis 3
RIMS2regulating synaptic membrane exocytosis 2
STX1Asyntaxin 1A (brain)
GLRBglycine receptor, beta
Query geneGeneGene descriptionEdge score
VAMP2VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
RIMS3RIMS3regulating synaptic membrane exocytosis 3
RIMS2RIMS2regulating synaptic membrane exocytosis 2
STX1ASTX1Asyntaxin 1A (brain)
GLRBGLRBglycine receptor, beta

Troyanskaya Laboratory - Princeton University