ASD

GO:0000578 embryonic axis specification (26)

GeneInput weightStandardRank
SMAD4--821
PTCH1--1972
PCSK6--1035
CXXC4--1490
SMAD6--2305
EPB41L5--2335
SMAD2--2694
TBX3--2958
C2CD3--2994
CITED1--3064
T--3286
WNT5A--3319
WNT1--4383
HOXB6--4560
TDGF1--6132
FRS2--7173
WNT7A--7312
HOXD8--7316
TDRD5--7375
RIPPLY2--7657
CTNNB10.519066
RIPPLY1--9472
GDF3--110819
TCF7L1--12273
PLD6--21953
FZD5--23249

Network

GO:0000578

Network
Enrichment
NameDescriptionExternal IDs
SMAD4SMAD family member 4 Entrez:4089  Ensembl: ENSG00000141646  HGNC: 6770  HPRD: 02995 
PTCH1patched 1 Entrez:5727  Ensembl: ENSG00000185920  HGNC: 9585  HPRD: 03200 
PCSK6proprotein convertase subtilisin/kexin type 6 Entrez:5046  HPRD: 01329  HGNC: 8569  Ensembl: ENSG00000140479 
CXXC4CXXC finger protein 4 Entrez:80319  HPRD: 16773  HGNC: 24593  Ensembl: ENSG00000168772 
SMAD6SMAD family member 6 Entrez:4091  Ensembl: ENSG00000137834  HPRD: 04240  HGNC: 6772 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SMAD4SMAD family member 4
PTCH1patched 1
PCSK6proprotein convertase subtilisin/kexin type 6
CXXC4CXXC finger protein 4
SMAD6SMAD family member 6
Query geneGeneGene descriptionEdge score
SMAD4SMAD4SMAD family member 4
PTCH1PTCH1patched 1
PCSK6PCSK6proprotein convertase subtilisin/kexin type 6
CXXC4CXXC4CXXC finger protein 4
SMAD6SMAD6SMAD family member 6

Troyanskaya Laboratory - Princeton University