ASD

GO:0043547 positive regulation of GTPase activity (139)

GeneInput weightStandardRank
GNAO1--4
PLCB1--148
RGS70.251135
ABR--160
AMPH--169
RGS4--178
GNAQ--189
RABGAP1--212
RASGRF1--335
NF10.251372
SFRP1--387
GSK3B--427
ARHGAP5--464
JUN--511
RAPGEF2--540
SIPA1L1--716
TSC10.251790
RGS6--805
SOS1--1810
RABGAP1L--846
RGS11--884
MAP2K10.251907
ARHGAP35--908
NDEL10.2511074
DLC1--1282
RALGAPA1--1420
RAP1GAP--1556
THY1--1580
RGS17--1702
DOCK40.2511765
BCR--11839
RASAL2--1889
TBC1D10B--1952
RASA1--1983
ELMOD1--2135
RAP1GDS1--2341
CHN2--2347
DOCK1--2675
PREX1--2760
RGS5--2795
VAV3--2908
FZD10--2957
PTK2B--3063
PREX2--3163
ARHGAP1--3304
DAB2IP--3482
CDKL5--13600
RASAL1--3614
ARHGAP26--13662
RGS12--3946
SYNGAP11.014039
AXIN2--14260
RGS20--4292
S1PR1--4301
AXIN1--14419
ARHGAP29--4559
RGS16--4657
ARAP3--4767
RALGAPA2--4803
RASA2--4877
MYO9B0.515005
RGS2--5095
RGS8--5148
RANGAP1--5328
RGS9--5332
ARHGAP6--5374
TBCD--5702
SNX18--5776
BIN1--6197
RHOG--6279
ALS2--16326
RGS22--6455
OPHN10.516584
RALBP1--6643
ERRFI1--6649
RGS13--6883
HTR2B--6992
GRHL3--7409
SYDE2--7604
FOXJ1--7628
WNT11--7820
PIN1--7940
CXCL13--8148
RASGRP3--8406
LRRK2--18802
RASA4--8961
RGS18--9348
TSC20.2519351
RAB3GAP1--9492
CCL11--9615
SYDE1--9690
TBC1D15--10227
RAB3GAP2--10501
RGS1--10535
SNX9--11169
ARHGAP8--11916
IQGAP1--12240
RGS14--12999
RGS21--13909
ARHGEF19--14560
CCL19--14578
TAX1BP3--15553
RASA3--15787
SNX13--15948
ARHGEF10L--17881
ARHGEF6--19241
EPHA2--119467
ALDH1A1--19488
CDC42EP2--19500
DOCK7--19597
RASAL3--19660
ARRB1--19906
PTPLAD1--20272
BNIP2--20381
RGS19--20558
ARHGAP15--21045
ARHGEF16--21200
SIPA1--21260
ARHGAP4--21362
ELMOD2--21506
CCL21--21829
CCL24--21868
RALGAPB--22093
RP2--122116
GMIP--22274
CCR7--22367
ARHGAP9--22481
GPR65--22555
CCL26--22814
ADAP2--22843
GNB2L1--23282
RGS3--23349
SCRIB--23676
TBC1D2--23738
NCKAP1L--23771
ARHGAP27--23975
RGS10--24612
ARAP1--24899
RACGAP1--24932

Network

GO:0043547

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
RGS7regulator of G-protein signaling 7 Entrez:6000  HGNC: 10003  HPRD: 03948  Ensembl: ENSG00000182901 
ABRactive BCR-related Entrez:29  HGNC: 81  HPRD: 02649  Ensembl: ENSG00000159842 
AMPHamphiphysin Entrez:273  HPRD: 02687  Ensembl: ENSG00000078053  HGNC: 471 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
RGS7regulator of G-protein signaling 7
ABRactive BCR-related
AMPHamphiphysin
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
RGS7RGS7regulator of G-protein signaling 7
ABRABRactive BCR-related
AMPHAMPHamphiphysin

Troyanskaya Laboratory - Princeton University