ASD

GO:0071396 cellular response to lipid (21)

GeneInput weightStandardRank
GRIN2A0.25166
PIK3R10.251150
LRP6--279
SFRP1--387
GRIN2B1.01763
BAD--1290
INHBB--2842
EGR1--3062
PTGDR--6801
TNFSF4--7262
CYP7A10.2517401
HMGCS1--7719
APOB--8737
AACS--9143
HMGCS2--12061
CPS1--112820
INHBA--16974
PDGFB--21071
E2F1--23057
ASS1--124321
CCNB1--25174

Network

GO:0071396

Network
Enrichment
NameDescriptionExternal IDs
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B Entrez:2904  Ensembl: ENSG00000150086  HPRD: 00697  HGNC: 4586 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
LRP6low density lipoprotein receptor-related protein 6
SFRP1secreted frizzled-related protein 1
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B
Query geneGeneGene descriptionEdge score
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
LRP6LRP6low density lipoprotein receptor-related protein 6
SFRP1SFRP1secreted frizzled-related protein 1
GRIN2BGRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B

Troyanskaya Laboratory - Princeton University