ASD

GO:0070936 protein K48-linked ubiquitination (32)

GeneInput weightStandardRank
TTC3--68
UBE3A0.251365
UBE2D3--528
UBE2D2--735
MARCH6--751
PARK20.251952
RNF4--973
UBE2E3--1210
UBE2G1--1334
UBE2R2--1579
CDC34--1592
UBE2K--1834
RNF6--12235
ITCH--2932
UBE2A0.2513019
RNF152--3719
UBE2B--4057
TNFAIP3--4469
ARIH2--4649
UBE2Q2--4678
UBE2G2--5131
UBE2H0.2515792
RNF5--7182
RNF146--7910
UBE2E1--7950
UBE2E2--14530
RNF216--17136
RNF187--20424
UBE2D4--24492
UBE2D1--24988
UBE2T--25295
UBE2C--25614

Network

GO:0070936

Network
Enrichment
NameDescriptionExternal IDs
TTC3tetratricopeptide repeat domain 3 Entrez:7267  HPRD: 03773  HGNC: 12393  Ensembl: ENSG00000182670 
UBE3Aubiquitin protein ligase E3A Entrez:7337  HPRD: 03375  HGNC: 12496  Ensembl: ENSG00000114062 
UBE2D3ubiquitin-conjugating enzyme E2D 3 Entrez:7323  Ensembl: ENSG00000109332  HPRD: 04269  HGNC: 12476 
UBE2D2ubiquitin-conjugating enzyme E2D 2 Entrez:7322  HPRD: 04268  HGNC: 12475  Ensembl: ENSG00000131508 
MARCH6membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase Entrez:10299  HPRD: 11095  HGNC: 30550  Ensembl: ENSG00000145495 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
TTC3tetratricopeptide repeat domain 3
UBE3Aubiquitin protein ligase E3A
UBE2D3ubiquitin-conjugating enzyme E2D 3
UBE2D2ubiquitin-conjugating enzyme E2D 2
MARCH6membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
Query geneGeneGene descriptionEdge score
TTC3TTC3tetratricopeptide repeat domain 3
UBE3AUBE3Aubiquitin protein ligase E3A
UBE2D3UBE2D3ubiquitin-conjugating enzyme E2D 3
UBE2D2UBE2D2ubiquitin-conjugating enzyme E2D 2
MARCH6MARCH6membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase

Troyanskaya Laboratory - Princeton University