ASD

GO:0032318 regulation of Ras GTPase activity (132)

GeneInput weightStandardRank
PAFAH1B10.25174
RASGRF1--335
NF10.251372
SFRP1--387
GSK3B--427
ARHGAP5--464
JUN--511
RAPGEF2--540
SIPA1L1--716
AGAP10.251766
TSC10.251790
SOS1--1810
RABGAP1L--846
MAP2K10.251907
ARHGAP35--908
NDEL10.2511074
DGKI--1124
FGD1--11182
DLC1--1282
RALGAPA1--1420
SPRY2--1454
RAP1GAP--1556
THY1--1580
ASAP2--1637
DOCK40.2511765
ARFGAP1--1852
RASAL2--1889
TBC1D10B--1952
RASA1--1983
AGAP2--2378
STMN3--2468
GIT1--2489
BCL6--2550
PREX1--2760
FZD10--2957
PTK2B--3063
ASAP1--3096
PREX2--3163
SMAP1--3243
ARHGAP1--3304
DAB2IP--3482
AGAP3--3546
ARAP2--3583
CDKL5--13600
RASAL1--3614
ARHGAP26--13662
SYNGAP11.014039
S1PR1--4301
AGAP7--4521
ARHGAP29--4559
ARAP3--4767
RALGAPA2--4803
AGAP4--4843
RASA2--4877
ACAP3--4921
DYNLT1--4976
MYO9B0.515005
MLST8--5028
RANGAP1--5328
ARHGAP6--5374
BVES--5886
RHOG--6279
ALS2--16326
ADAP1--6573
OPHN10.516584
RALBP1--6643
ERRFI1--6649
HTR2B--6992
GRHL3--7409
FGD4--17457
SYDE2--7604
FOXJ1--7628
WNT11--7820
PIN1--7940
AGFG1--8117
CXCL13--8148
AGAP8--8245
RASGRP3--8406
FGD3--8790
RASA4--8961
AGAP5--9202
AGAP11--9307
RAB3GAP1--9492
CCL11--9615
SYDE1--9690
TBC1D15--10227
FGD5--10619
SPRY1--10636
AGAP9--10698
ARHGAP8--11916
ASAP3--11995
FGD6--12199
FICD--13795
SMAP2--14426
ARHGEF19--14560
CCL19--14578
TAX1BP3--15553
RASA3--15787
AGAP10--16012
CTGLF11P--17728
ARHGEF10L--17881
ARFGAP2--18897
AGAP6--19286
EPHA2--119467
ALDH1A1--19488
CDC42EP2--19500
DOCK7--19597
RASAL3--19660
FGD2--20103
ACAP2--20167
ARHGAP15--21045
AGFG2--21063
MTOR--21095
ARHGEF16--21200
SIPA1--21260
ARHGAP4--21362
CCL21--21829
CCL24--21868
RALGAPB--22093
GMIP--22274
CCR7--22367
GPR65--22555
GIT2--22751
CCL26--22814
ADAP2--22843
SCRIB--23676
TBC1D2--23738
NCKAP1L--23771
ARHGAP27--23975
ARAP1--24899
ACAP1--25044
ARFGAP3--25472

Network

GO:0032318

Network
Enrichment
NameDescriptionExternal IDs
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Entrez:5048  HGNC: 8574  HPRD: 03329  Ensembl: ENSG00000007168 
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1 Entrez:5923  HGNC: 9875  Ensembl: ENSG00000058335 
NF1neurofibromin 1 Entrez:4763  HGNC: 7765  HPRD: 01203  Ensembl: ENSG00000196712 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
GSK3Bglycogen synthase kinase 3 beta Entrez:2932  Ensembl: ENSG00000082701  HPRD: 05418  HGNC: 4617 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
NF1neurofibromin 1
SFRP1secreted frizzled-related protein 1
GSK3Bglycogen synthase kinase 3 beta
Query geneGeneGene descriptionEdge score
PAFAH1B1PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
RASGRF1RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
NF1NF1neurofibromin 1
SFRP1SFRP1secreted frizzled-related protein 1
GSK3BGSK3Bglycogen synthase kinase 3 beta

Troyanskaya Laboratory - Princeton University