ASD

GO:0002088 lens development in camera-type eye (46)

GeneInput weightStandardRank
SOX11--96
HIPK1--311
MEIS1--450
PAX60.251544
SMAD3--823
SHROOM2--937
PROX1--997
HIPK2--1051
PVRL3--1324
WNT2B--1673
WNT20.2512299
SIX3--12494
FGFR3--12640
SKIL--2889
SKI--2904
FZR1--2920
WNT5A--3319
CDON--3487
FOXE3--13688
CRYGC--3739
DLG1--3822
FOXE1--13900
PVRL1--4430
CRYGA--4941
CRYBA1--5325
NF2--15991
MIP--6085
BMP4--16499
WNT7B--7113
WNT7A--7312
BFSP1--7889
CRYGS--8422
BFSP2--8586
CTNNB10.519066
CRYGB--9219
SLC7A11--9692
CRYAA--10509
PYGO2--11014
GJA8--11252
WNT5B--15534
PITX30.25119326
TGFB10.25120135
TDRD7--20348
SIX5--121823
CASP6--23087
CRYAB--124965

Network

GO:0002088

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
HIPK1homeodomain interacting protein kinase 1 Entrez:204851  HGNC: 19006  Ensembl: ENSG00000163349  HPRD: 06418 
MEIS1Meis homeobox 1 Entrez:4211  HGNC: 7000  Ensembl: ENSG00000143995  HPRD: 03442 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
HIPK1homeodomain interacting protein kinase 1
MEIS1Meis homeobox 1
PAX6paired box 6
SMAD3SMAD family member 3
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
HIPK1HIPK1homeodomain interacting protein kinase 1
MEIS1MEIS1Meis homeobox 1
PAX6PAX6paired box 6
SMAD3SMAD3SMAD family member 3

Troyanskaya Laboratory - Princeton University