ASD

GO:0045727 positive regulation of translation (44)

GeneInput weightStandardRank
SOX4--250
EP300--1318
EIF4G3--1083
MAPK1--1128
RPS6KB1--1521
PAIP1--1686
CIRBP--2440
PTK2B--3063
UHMK1--3601
BARHL2--4545
SAMD4A--4734
PIWIL2--4828
UPF3A--5542
DAZ1--6267
MAPK30.2516426
CD28--6931
DAZL--7043
LIN28A--7070
EIF4A3--7597
BCL3--7998
POLDIP3--8198
BOLL--8978
PABPC1--9200
UCN--10358
SERP1--11460
RHOC--11655
EIF5A2--12630
IL6--112695
FAM129A--13686
TNF0.25115243
MTOR--21095
UPF3B--21339
SBDS--21769
EIF5AL1--22509
RBM3--22670
EIF5A--22674
CCL5--23042
RPS6KB2--23226
ABCF1--23393
THBS1--24444
WIBG--24922
RPS27L--25183
EIF2B5--25325
RPS4X--25564

Network

GO:0045727

Network
Enrichment
NameDescriptionExternal IDs
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
EP300E1A binding protein p300 Entrez:2033  Ensembl: ENSG00000100393  HGNC: 3373  HPRD: 04078 
EIF4G3eukaryotic translation initiation factor 4 gamma, 3 Entrez:8672  Ensembl: ENSG00000075151  HGNC: 3298  HPRD: 06802 
MAPK1mitogen-activated protein kinase 1 Entrez:5594  HPRD: 01496  Ensembl: ENSG00000100030  HGNC: 6871 
RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1 Entrez:6198  Ensembl: ENSG00000108443  HGNC: 10436  HPRD: 10202 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX4SRY (sex determining region Y)-box 4
EP300E1A binding protein p300
EIF4G3eukaryotic translation initiation factor 4 gamma, 3
MAPK1mitogen-activated protein kinase 1
RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1
Query geneGeneGene descriptionEdge score
SOX4SOX4SRY (sex determining region Y)-box 4
EP300EP300E1A binding protein p300
EIF4G3EIF4G3eukaryotic translation initiation factor 4 gamma, 3
MAPK1MAPK1mitogen-activated protein kinase 1
RPS6KB1RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1

Troyanskaya Laboratory - Princeton University