ASD

GO:0017144 drug metabolic process (27)

GeneInput weightStandardRank
NOS10.251853
CYP2E1--1710
CYP2A6--12792
BCHE--2809
CYP2C8--3090
CYP2C9--3660
NECAB2--3718
CYP2C19--4815
CYP1A10.2515067
NECAB1--5228
CYP2B6--5346
CYP1A2--6074
UGT1A8--6979
NECAB3--8326
NR1I2--9659
CYP3A4--9925
FMO3--11428
UGT1A7--18533
UGT1A9--19030
CYP3A5--119412
FMO2--19964
DCK--20599
UGT1A1--122467
EPHX2--23371
CBR1--23598
CYP2D60.25124035
CAD--24868

Network

GO:0017144

Network
Enrichment
NameDescriptionExternal IDs
NOS1nitric oxide synthase 1 (neuronal) Entrez:4842  HPRD: 01226  HGNC: 7872  Ensembl: ENSG00000089250 
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1 Entrez:1571  Ensembl: ENSG00000130649  HPRD: 11813  HGNC: 2631 
CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6 Entrez:1548  Ensembl: ENSG00000255974  HPRD: 00420  HGNC: 2610 
BCHEbutyrylcholinesterase Entrez:590  Ensembl: ENSG00000114200  HGNC: 983  HPRD: 01519 
CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 8 Entrez:1558  HGNC: 2622  Ensembl: ENSG00000138115  HPRD: 03083 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NOS1nitric oxide synthase 1 (neuronal)
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6
BCHEbutyrylcholinesterase
CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 8
Query geneGeneGene descriptionEdge score
NOS1NOS1nitric oxide synthase 1 (neuronal)
CYP2E1CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2A6CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6
BCHEBCHEbutyrylcholinesterase
CYP2C8CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 8

Troyanskaya Laboratory - Princeton University