ASD: Genome-wide prediction of autism-associated genes

Gene	Input weight	Standard	Rank
CNR1	0.25	1	29
GRIN2A	0.25	1	66
SLC6A1	0.25	1	313
GRIN2B	1.0	1	763
DRD1	0.25	1	899
DRD5	0.25	1	1103
DPYSL2	-	-	2672
PTK2B	-	-	3063
CDK5	0.25	1	3194
TACR3	-	-	3564
DRD2	0.25	1	3749
ABAT	0.25	1	4348
DRD3	0.25	1	4349
ADRA1B	0.25	1	4946
OXTR	0.5	1	6388
SLC18A2	-	-	6423
DRD4	0.25	1	7021
SLC6A3	0.5	1	7659
HTR1B	0.25	1	8092
OXT	0.25	1	11176
CHRNB2	0.25	1	20216
HNMT	-	-	21489
SMPD1	-	-1	25116

Network

GO:0042220

Minimum relationship confidence:

Maximum number of genes:

Name	Description	External IDs
CNR1	cannabinoid receptor 1 (brain)	Entrez:1268 HGNC: 2159 Ensembl: ENSG00000118432 HPRD: 00259
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	Entrez:2903 HGNC: 4585 Ensembl: ENSG00000183454 HPRD: 00698
SLC6A1	solute carrier family 6 (neurotransmitter transporter), member 1	Entrez:6529 Ensembl: ENSG00000157103 HGNC: 11042 HPRD: 00664
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	Entrez:2904 Ensembl: ENSG00000150086 HPRD: 00697 HGNC: 4586
DRD1	dopamine receptor D1	Entrez:1812 HPRD: 00538 HGNC: 3020 Ensembl: ENSG00000184845

Geneset	Type	Freq. (Network vs Genome)	P-Value (FDR Corrected)	Genes

Gene	Description	Avg. edge score to query	Rank	In geneset	In query
CNR1	cannabinoid receptor 1 (brain)
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A
SLC6A1	solute carrier family 6 (neurotransmitter transporter), member 1
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B
DRD1	dopamine receptor D1

Query gene	Gene	Gene description	Edge score
CNR1	CNR1	cannabinoid receptor 1 (brain)
GRIN2A	GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A
SLC6A1	SLC6A1	solute carrier family 6 (neurotransmitter transporter), member 1
GRIN2B	GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B
DRD1	DRD1	dopamine receptor D1