ASD

GO:0021522 spinal cord motor neuron differentiation (17)

GeneInput weightStandardRank
SOX4--250
CACNA1A--1270
PAX60.251544
NKX2-2--1120
ISL1--1974
GIGYF2--12267
MDGA20.2512720
HOXD10--4534
NKX6-1--4665
NKX6-2--4791
HOXC10--5156
PHOX2A--5462
MNX1--5812
GLI3--16261
CLN8--16415
LHX4--7529
ABT1--22077

Network

GO:0021522

Network
Enrichment
NameDescriptionExternal IDs
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
NKX2-2NK2 homeobox 2 Entrez:4821  Ensembl: ENSG00000125820  HGNC: 7835  HPRD: 05213 
ISL1ISL LIM homeobox 1 Entrez:3670  HGNC: 6132  Ensembl: ENSG00000016082  HPRD: 02650 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX4SRY (sex determining region Y)-box 4
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
PAX6paired box 6
NKX2-2NK2 homeobox 2
ISL1ISL LIM homeobox 1
Query geneGeneGene descriptionEdge score
SOX4SOX4SRY (sex determining region Y)-box 4
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
PAX6PAX6paired box 6
NKX2-2NKX2-2NK2 homeobox 2
ISL1ISL1ISL LIM homeobox 1

Troyanskaya Laboratory - Princeton University