ASD

GO:0016579 protein deubiquitination (55)

GeneInput weightStandardRank
PSMD14--104
USP34--231
OTUB1--431
USP33--542
USP9X--554
USP7--573
UCHL1--1675
USP46--708
USP1--917
USP11--1197
BAP1--1370
USP22--1419
USP12--1581
USP6--1693
USP42--1978
TRRAP--2163
USP47--2202
WDR48--2380
ATXN7--12540
YOD1--2571
TAF10--2986
USP21--3007
ENY2--3018
ATXN3L--3329
USP44--3406
ZRANB1--3481
USP10--3561
USP15--3748
USP3--3777
USP37--3840
USP2--3856
USP16--3898
USP32--4210
TNFAIP3--4469
CYLD--14624
USP20--4986
OTUD7B--5199
ATXN7L3--6464
USP9Y--16508
UIMC1--6729
USP4--7808
USP8--8039
USP26--8427
USP5--9852
BABAM1--9983
OTUB2--10222
MYSM1--10420
JOSD2--13946
USP17L2--14660
USP28--15068
SUPT3H--20053
USP19--20335
BRCC3--20674
KAT2A--21262
UCHL5--22745

Network

GO:0016579

Network
Enrichment
NameDescriptionExternal IDs
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
USP34ubiquitin specific peptidase 34 Entrez:9736  HGNC: 20066  HPRD: 11665  Ensembl: ENSG00000115464 
OTUB1OTU domain, ubiquitin aldehyde binding 1 Entrez:55611  HPRD: 08493  HGNC: 23077 
USP33ubiquitin specific peptidase 33 Entrez:23032  HPRD: 10297  Ensembl: ENSG00000077254  HGNC: 20059 
USP9Xubiquitin specific peptidase 9, X-linked Entrez:8239  HGNC: 12632  HPRD: 02091  Ensembl: ENSG00000124486 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
USP34ubiquitin specific peptidase 34
OTUB1OTU domain, ubiquitin aldehyde binding 1
USP33ubiquitin specific peptidase 33
USP9Xubiquitin specific peptidase 9, X-linked
Query geneGeneGene descriptionEdge score
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
USP34USP34ubiquitin specific peptidase 34
OTUB1OTUB1OTU domain, ubiquitin aldehyde binding 1
USP33USP33ubiquitin specific peptidase 33
USP9XUSP9Xubiquitin specific peptidase 9, X-linked

Troyanskaya Laboratory - Princeton University