ASD

GO:0009950 dorsal/ventral axis specification (21)

GeneInput weightStandardRank
LRP6--279
SFRP1--387
PAX60.251544
BMPR1A--1140
CXXC4--1490
WNT2B--1673
WNT20.2512299
SMAD6--2305
SMAD2--2694
WNT5A--3319
VAX2--3553
AXIN2--14260
AXIN1--14419
WNT3--4613
CTNNB10.519066
LRP5--19420
MDFI--13519
WNT5B--15534
SENP2--21704
LRP5L--22282
FZD5--23249

Network

GO:0009950

Network
Enrichment
NameDescriptionExternal IDs
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
BMPR1Abone morphogenetic protein receptor, type IA Entrez:657  HGNC: 1076  Ensembl: ENSG00000107779  HPRD: 03192 
CXXC4CXXC finger protein 4 Entrez:80319  HPRD: 16773  HGNC: 24593  Ensembl: ENSG00000168772 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
LRP6low density lipoprotein receptor-related protein 6
SFRP1secreted frizzled-related protein 1
PAX6paired box 6
BMPR1Abone morphogenetic protein receptor, type IA
CXXC4CXXC finger protein 4
Query geneGeneGene descriptionEdge score
LRP6LRP6low density lipoprotein receptor-related protein 6
SFRP1SFRP1secreted frizzled-related protein 1
PAX6PAX6paired box 6
BMPR1ABMPR1Abone morphogenetic protein receptor, type IA
CXXC4CXXC4CXXC finger protein 4

Troyanskaya Laboratory - Princeton University