ASD

GO:0016486 peptide hormone processing (25)

GeneInput weightStandardRank
PCSK2--217
PCSK1--898
PCSK6--1035
SCG50.2511173
PCSK1N--2078
CPE--2149
CGA0.2512258
TSHB--2368
FURIN--4605
CORIN--4683
NGF0.2516229
REN--17086
CGB7--9343
ECE2--10348
PCSK7--10515
FSHB0.25112923
PCSK5--13062
CGB5--14205
POMC0.25114990
CGB8--15211
LHB0.25119520
BACE2--20446
ECE1--120540
CGB--22000
ATP6AP2--25361

Network

GO:0016486

Network
Enrichment
NameDescriptionExternal IDs
PCSK2proprotein convertase subtilisin/kexin type 2 Entrez:5126  Ensembl: ENSG00000125851  HGNC: 8744  HPRD: 01202 
PCSK1proprotein convertase subtilisin/kexin type 1 Entrez:5122  HGNC: 8743  HPRD: 01201  Ensembl: ENSG00000175426 
PCSK6proprotein convertase subtilisin/kexin type 6 Entrez:5046  HPRD: 01329  HGNC: 8569  Ensembl: ENSG00000140479 
SCG5secretogranin V (7B2 protein) Entrez:6447  HPRD: 01410  HGNC: 10816  Ensembl: ENSG00000166922 
PCSK1Nproprotein convertase subtilisin/kexin type 1 inhibitor Entrez:27344  HGNC: 17301  HPRD: 02320  Ensembl: ENSG00000102109 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PCSK2proprotein convertase subtilisin/kexin type 2
PCSK1proprotein convertase subtilisin/kexin type 1
PCSK6proprotein convertase subtilisin/kexin type 6
SCG5secretogranin V (7B2 protein)
PCSK1Nproprotein convertase subtilisin/kexin type 1 inhibitor
Query geneGeneGene descriptionEdge score
PCSK2PCSK2proprotein convertase subtilisin/kexin type 2
PCSK1PCSK1proprotein convertase subtilisin/kexin type 1
PCSK6PCSK6proprotein convertase subtilisin/kexin type 6
SCG5SCG5secretogranin V (7B2 protein)
PCSK1NPCSK1Nproprotein convertase subtilisin/kexin type 1 inhibitor

Troyanskaya Laboratory - Princeton University