ASD

GO:0045823 positive regulation of heart contraction (21)

GeneInput weightStandardRank
TGFB2--834
ADRB1--1057
EDN3--11577
CHRNA70.511837
ADRA1A--1858
HCN2--3542
TACR3--3564
AVPR1A0.513803
GSK3A--4141
ADRA1B0.2514946
ATP1A10.2515927
NKX2-50.2518486
AVPR1B0.2518546
EDN1--9540
GLP1R--9893
EDN2--18677
CHRFAM7A--20694
ADM--21106
ADRB20.25123251
TPM1--124247
ADA0.5124751

Network

GO:0045823

Network
Enrichment
NameDescriptionExternal IDs
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
ADRB1adrenoceptor beta 1 Entrez:153  HGNC: 285  Ensembl: ENSG00000043591  HPRD: 00181 
EDN3endothelin 3 Entrez:1908  HGNC: 3178  Ensembl: ENSG00000124205  HPRD: 00570 
CHRNA7cholinergic receptor, nicotinic, alpha 7 (neuronal) Entrez:1139  HPRD: 00339  HGNC: 1960 
ADRA1Aadrenoceptor alpha 1A Entrez:148  HGNC: 277  Ensembl: ENSG00000120907  HPRD: 00081 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
TGFB2transforming growth factor, beta 2
ADRB1adrenoceptor beta 1
EDN3endothelin 3
CHRNA7cholinergic receptor, nicotinic, alpha 7 (neuronal)
ADRA1Aadrenoceptor alpha 1A
Query geneGeneGene descriptionEdge score
TGFB2TGFB2transforming growth factor, beta 2
ADRB1ADRB1adrenoceptor beta 1
EDN3EDN3endothelin 3
CHRNA7CHRNA7cholinergic receptor, nicotinic, alpha 7 (neuronal)
ADRA1AADRA1Aadrenoceptor alpha 1A

Troyanskaya Laboratory - Princeton University