ASD

GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway (11)

GeneInput weightStandardRank
SFRP1--387
RAC1--1617
VANGL2--1793
DVL3--2090
WNT5A--3319
DVL2--6546
GRHL3--7409
WNT9B--8217
DVL1P1--18731
DVL1--18924
FZD6--19921

Network

GO:0060071

Network
Enrichment
NameDescriptionExternal IDs
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Entrez:5879  Ensembl: ENSG00000136238  HPRD: 03627  HGNC: 9801 
VANGL2VANGL planar cell polarity protein 2 Entrez:57216  Ensembl: ENSG00000162738  HGNC: 15511  HPRD: 02758 
DVL3dishevelled segment polarity protein 3 Entrez:1857  Ensembl: ENSG00000161202  HGNC: 3087  HPRD: 03222 
WNT5Awingless-type MMTV integration site family, member 5A Entrez:7474  Ensembl: ENSG00000114251  HPRD: 01293  HGNC: 12784 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SFRP1secreted frizzled-related protein 1
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
VANGL2VANGL planar cell polarity protein 2
DVL3dishevelled segment polarity protein 3
WNT5Awingless-type MMTV integration site family, member 5A
Query geneGeneGene descriptionEdge score
SFRP1SFRP1secreted frizzled-related protein 1
RAC1RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
VANGL2VANGL2VANGL planar cell polarity protein 2
DVL3DVL3dishevelled segment polarity protein 3
WNT5AWNT5Awingless-type MMTV integration site family, member 5A

Troyanskaya Laboratory - Princeton University