ASD

GO:0043951 negative regulation of cAMP-mediated signaling (5)

GeneInput weightStandardRank
CDC34--1592
MGRN1--2277
PDE3B--3819
UBE2B--4057
CRHR2--5751

Network

GO:0043951

Network
Enrichment
NameDescriptionExternal IDs
CDC34cell division cycle 34 Entrez:997  HGNC: 1734  Ensembl: ENSG00000099804  HPRD: 00306 
MGRN1mahogunin ring finger 1, E3 ubiquitin protein ligase Entrez:23295  HPRD: 07397  HGNC: 20254  Ensembl: ENSG00000102858 
PDE3Bphosphodiesterase 3B, cGMP-inhibited Entrez:5140  HGNC: 8779  Ensembl: ENSG00000152270  HPRD: 03626 
UBE2Bubiquitin-conjugating enzyme E2B Entrez:7320  Ensembl: ENSG00000119048  HPRD: 01533  HGNC: 12473 
CRHR2corticotropin releasing hormone receptor 2 Entrez:1395  HGNC: 2358  HPRD: 03614 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CDC34cell division cycle 34
MGRN1mahogunin ring finger 1, E3 ubiquitin protein ligase
PDE3Bphosphodiesterase 3B, cGMP-inhibited
UBE2Bubiquitin-conjugating enzyme E2B
CRHR2corticotropin releasing hormone receptor 2
Query geneGeneGene descriptionEdge score
CDC34CDC34cell division cycle 34
MGRN1MGRN1mahogunin ring finger 1, E3 ubiquitin protein ligase
PDE3BPDE3Bphosphodiesterase 3B, cGMP-inhibited
UBE2BUBE2Bubiquitin-conjugating enzyme E2B
CRHR2CRHR2corticotropin releasing hormone receptor 2

Troyanskaya Laboratory - Princeton University