ASD

GO:0007205 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway (38)

GeneInput weightStandardRank
GAP43--60
GRM50.251240
DGKZ--547
DGKI--1124
DGKB--1341
PARD3--1845
CCK0.2511899
SPECC1L--1912
DGKG--2155
DGKE--3651
EDNRA--13857
DGKD--4786
SPHK2--5120
CERK--5270
DGKH--6642
CHRM1--6796
PLCE1--6929
HTR2B--6992
PRKD3--7603
IL2--7838
HTR1B0.2518092
ADORA2A0.2518408
EDN1--9540
DGKQ--9874
PICK1--11315
HCRT0.25111633
MS4A2--13136
CERKL--114754
DGKK--16992
BDKRB1--18217
EDN2--18677
AZU1--18895
F2R--20036
AGK--21412
LRP1--22276
DGKA--23016
SPHK1--24069
PPAP2A--25298

Network

GO:0007205

Network
Enrichment
NameDescriptionExternal IDs
GAP43growth associated protein 43 Entrez:2596  Ensembl: ENSG00000172020  HPRD: 01198  HGNC: 4140 
GRM5glutamate receptor, metabotropic 5 Entrez:2915  HGNC: 4597  Ensembl: ENSG00000168959 
DGKZdiacylglycerol kinase, zeta Entrez:8525  HPRD: 03260  HGNC: 2857  Ensembl: ENSG00000149091 
DGKIdiacylglycerol kinase, iota Entrez:9162  HPRD: 07238  HGNC: 2855  Ensembl: ENSG00000157680 
DGKBdiacylglycerol kinase, beta 90kDa Entrez:1607  HGNC: 2850  HPRD: 06819  Ensembl: ENSG00000136267 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GAP43growth associated protein 43
GRM5glutamate receptor, metabotropic 5
DGKZdiacylglycerol kinase, zeta
DGKIdiacylglycerol kinase, iota
DGKBdiacylglycerol kinase, beta 90kDa
Query geneGeneGene descriptionEdge score
GAP43GAP43growth associated protein 43
GRM5GRM5glutamate receptor, metabotropic 5
DGKZDGKZdiacylglycerol kinase, zeta
DGKIDGKIdiacylglycerol kinase, iota
DGKBDGKBdiacylglycerol kinase, beta 90kDa

Troyanskaya Laboratory - Princeton University