ASD

GO:0051494 negative regulation of cytoskeleton organization (70)

GeneInput weightStandardRank
MAPT0.25176
MAP2--106
APC0.251266
MAPRE1--331
STMN2--343
CLASP2--375
MAP1B--403
PFN2--551
SLIT2--659
SNCA--1667
CLIP3--730
SHROOM2--937
PARK20.251952
CLASP1--955
KANK1--1150
DLC1--1282
SPTAN1--11287
DMTN--1465
SPTBN4--1647
ARHGEF2--1819
SPTBN2--11935
TMSB10--2139
CAPZB--2179
ADD2--2388
ADD1--12876
TMSB15A--2947
TMSB15B--3139
MAP3K1--13381
SPTB--3478
SPTBN1--3627
INPP5J--3690
S1PR1--4301
CAPZA2--4483
RDX--14697
CAPZA1--4983
SPTBN5--5319
ARHGAP6--5374
TBCD--5702
TMSB4X--6302
SPTA1--16958
AVIL--7943
CAPZA3--8396
KATNB1--8593
MID1IP1--9080
STMN1--9278
SCIN--9620
TWF1--11060
ESPN--112835
TMSB4Y--13524
TRIM54--13879
TMSB4XP8--14081
CAV3--115414
HDAC6--16779
TMSB4XP4--17717
MAP4--20072
CORO1A--20339
CAPG--20663
MAP6D1--20928
CDK5RAP2--121330
SBDS--21769
VIL10.5122243
VILL--22283
TWF2--23010
FKBP4--23829
GSN--124007
TRIOBP--124113
LIMA1--24553
BRCA1--124573
ARAP1--24899
CCNB1--25174

Network

GO:0051494

Network
Enrichment
NameDescriptionExternal IDs
MAPTmicrotubule-associated protein tau Entrez:4137  HGNC: 6893  Ensembl: ENSG00000186868  HPRD: 01142 
MAP2microtubule-associated protein 2 Entrez:4133  HPRD: 01140  HGNC: 6839  Ensembl: ENSG00000078018 
APCadenomatous polyposis coli Entrez:324  HGNC: 583  HPRD: 01439  Ensembl: ENSG00000134982 
MAPRE1microtubule-associated protein, RP/EB family, member 1 Entrez:22919  HGNC: 6890  HPRD: 04379  Ensembl: ENSG00000101367 
STMN2stathmin-like 2 Entrez:11075  HGNC: 10577  HPRD: 09003  Ensembl: ENSG00000104435 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAPTmicrotubule-associated protein tau
MAP2microtubule-associated protein 2
APCadenomatous polyposis coli
MAPRE1microtubule-associated protein, RP/EB family, member 1
STMN2stathmin-like 2
Query geneGeneGene descriptionEdge score
MAPTMAPTmicrotubule-associated protein tau
MAP2MAP2microtubule-associated protein 2
APCAPCadenomatous polyposis coli
MAPRE1MAPRE1microtubule-associated protein, RP/EB family, member 1
STMN2STMN2stathmin-like 2

Troyanskaya Laboratory - Princeton University