ASD

GO:0051047 positive regulation of secretion (175)

GeneInput weightStandardRank
SNAP250.25126
PLCB1--148
SOX11--96
CREB1--100
CADPS--133
PRKCE--204
SOX4--250
GABBR10.251264
SLC6A10.251313
EP300--1318
CADM10.251391
NR3C1--496
STX1A0.251512
NNAT--543
CRH--563
CRHR1--589
SNCA--1667
PEX5L--686
TAC10.251726
MGEA5--732
GRIN2B1.01763
CCKBR--794
TGFB2--834
PCSK1--898
ADORA1--960
ACVR2A--965
ADRB1--1057
BAD--1290
IRS2--11300
IRS1--11374
MIF0.2511552
EDN3--11577
SPECC1L--1912
CARTPT0.2511957
ISL1--1974
ACHE--2025
GATA3--2376
NCS1--2628
GCK--12660
DPYSL2--2672
SCAMP50.2512682
RTN4--2735
INHBB--2842
GLRA1--2965
CDK50.2513194
WNT5A--3319
TRH--3416
RBP4--3448
GAB2--3496
TCF7L20.513548
SLC18A1--3611
SLC30A8--13644
STXBP5--3733
DRD20.2513749
AVPR1A0.513803
CACNA1H1.013855
GLUD1--14146
IRF3--4175
GHRHR--4237
P2RY1--4342
IL1A--4651
GDNF--14658
NKX6-1--4665
INHA--4765
NLRP30.2514959
GCG--5190
CAPN10--5208
TNFSF11--15271
TNFRSF11A--15293
OXCT1--5813
ADRBK1--6028
PLA2G1B--6059
NR1H2--6183
PFKFB2--6327
GIP--6352
OXTR0.516388
RAB8B--6706
TNFSF15--6782
KNG1--6802
HTR2B--6992
APLN--7041
TRPV10.2517162
TNFSF4--7262
NPPB--7334
GHRH--7478
LACRT--7733
CXCL12--7802
IL2--7838
P2RX7--7888
RPH3AL--8235
ADORA2A0.2518408
AVPR1B0.2518546
AACS--9143
CHIA--9216
GHRL0.2519242
KISS1R--9434
IL10--19513
EDN1--9540
SCIN--9620
IL5--9669
GLP1R--9893
HCAR2--10053
GIPR--10369
UCN3--10665
IL1B--110818
PYDC1--11053
DOC2B--11084
OXT0.25111176
FFAR1--11393
SERP1--11460
TACR1--11618
IL26--11645
BLK--111743
CCKAR--11747
LEP0.25111864
CLEC6A--12440
IL6--112695
IFNG--112827
VEGFC--12850
IL13--12888
TGFB3--113097
MS4A2--13136
AGT--113305
CRTAM--13317
AVP--113439
IL33--13620
PSMD9--13911
CCL19--14578
ZP4--14747
CLEC9A--14752
TAC4--15219
TNF0.25115243
PRKCQ--15381
GLMN--16462
INHBA--16974
ZP3--17443
PINK1--118609
EDN2--18677
ADORA2B--19522
NLRP12--19807
F2RL1--19969
F2R--20036
PLA2G10--20040
TGFB10.25120135
CHRNB20.25120216
NLRP1--20532
IL4R--20610
TNFRSF4--20689
PANX1--21011
UNC13D--121158
NR0B2--121425
CD380.25121442
FCER1G--21507
NOD2--121514
NLRP2--21787
ADAM8--21797
C5--122004
INS--122047
LIF--22134
NMU--22143
PYCARD--22145
P2RX4--22325
AQP1--22433
SAA1--22464
CARD8--22573
TRIM16--22841
PLD2--22908
CD14--22990
SYK--23906
P2RY2--24088
SAA2--24171
ANG--124879
NPR1--24948
KCNN4--24952
ADAM9--125221

Network

GO:0051047

Network
Enrichment
NameDescriptionExternal IDs
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
CREB1cAMP responsive element binding protein 1 Entrez:1385  HGNC: 2345  HPRD: 00442  Ensembl: ENSG00000118260 
CADPSCa++-dependent secretion activator Entrez:8618  Ensembl: ENSG00000163618  HGNC: 1426  HPRD: 05236 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SNAP25synaptosomal-associated protein, 25kDa
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
SOX11SRY (sex determining region Y)-box 11
CREB1cAMP responsive element binding protein 1
CADPSCa++-dependent secretion activator
Query geneGeneGene descriptionEdge score
SNAP25SNAP25synaptosomal-associated protein, 25kDa
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
SOX11SOX11SRY (sex determining region Y)-box 11
CREB1CREB1cAMP responsive element binding protein 1
CADPSCADPSCa++-dependent secretion activator

Troyanskaya Laboratory - Princeton University