ASD

GO:0071347 cellular response to interleukin-1 (24)

GeneInput weightStandardRank
PLCB1--148
RPS6KA5--359
SFRP1--387
VLDLR0.251574
SOX9--1970
RBMX--1730
EGR1--3062
MAPK30.2516426
CYP11A10.2518063
EDN1--9540
RPS6KA4--10148
IRF1--111641
MYLK3--12362
IRAK3--14633
IRAK2--15024
CHI3L1--20463
KLF2--20711
IRAK1--21640
CCL2--23209
ICAM1--23720
IL1R1--23779
P2RY2--24088
MMP9--24369
LCN2--25233

Network

GO:0071347

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5 Entrez:9252  Ensembl: ENSG00000100784  HPRD: 06789  HGNC: 10434 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
VLDLRvery low density lipoprotein receptor Entrez:7436  Ensembl: ENSG00000147852  HGNC: 12698  HPRD: 01895 
SOX9SRY (sex determining region Y)-box 9 Entrez:6662  HPRD: 06427  HGNC: 11204  Ensembl: ENSG00000125398 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5
SFRP1secreted frizzled-related protein 1
VLDLRvery low density lipoprotein receptor
SOX9SRY (sex determining region Y)-box 9
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
RPS6KA5RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5
SFRP1SFRP1secreted frizzled-related protein 1
VLDLRVLDLRvery low density lipoprotein receptor
SOX9SOX9SRY (sex determining region Y)-box 9

Troyanskaya Laboratory - Princeton University