ASD

GO:0048260 positive regulation of receptor-mediated endocytosis (21)

GeneInput weightStandardRank
SYNJ1--156
BICD1--552
HNRNPK--885
CBL--1478
SGIP1--1665
HIP1--1797
DRD20.2513749
ANGPT1--4182
WNT3A--4747
SCYL2--7130
SFRP4--7310
PCSK9--10760
VTN--13271
APOA5--113831
PPT1--113834
CCL19--14578
SELE--14642
CCL21--21829
PLD2--22908
SERPINE10.25125055
LDLRAP1--25289

Network

GO:0048260

Network
Enrichment
NameDescriptionExternal IDs
SYNJ1synaptojanin 1 Entrez:8867  Ensembl: ENSG00000159082  HGNC: 11503  HPRD: 09182 
BICD1bicaudal D homolog 1 (Drosophila) Entrez:636  Ensembl: ENSG00000151746  HGNC: 1049  HPRD: 03730 
HNRNPKheterogeneous nuclear ribonucleoprotein K Entrez:3190  HGNC: 5044  Ensembl: ENSG00000165119  HPRD: 02834 
CBLCbl proto-oncogene, E3 ubiquitin protein ligase Entrez:867  HPRD: 01320  Ensembl: ENSG00000110395  HGNC: 1541 
SGIP1SH3-domain GRB2-like (endophilin) interacting protein 1 Entrez:84251  Ensembl: ENSG00000118473  HPRD: 10910  HGNC: 25412 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYNJ1synaptojanin 1
BICD1bicaudal D homolog 1 (Drosophila)
HNRNPKheterogeneous nuclear ribonucleoprotein K
CBLCbl proto-oncogene, E3 ubiquitin protein ligase
SGIP1SH3-domain GRB2-like (endophilin) interacting protein 1
Query geneGeneGene descriptionEdge score
SYNJ1SYNJ1synaptojanin 1
BICD1BICD1bicaudal D homolog 1 (Drosophila)
HNRNPKHNRNPKheterogeneous nuclear ribonucleoprotein K
CBLCBLCbl proto-oncogene, E3 ubiquitin protein ligase
SGIP1SGIP1SH3-domain GRB2-like (endophilin) interacting protein 1

Troyanskaya Laboratory - Princeton University